Celia O. G.
- Country
- Spain
- Department
- Departamento de Neurología
Research Overview
- Efficacy and Safety of Remibrutinib in Patients with Secondary Progressive Multiple Sclerosis: A Phase III, Randomized, Double-Blind, Placebo-Controlled Study
- Evaluation of Sodium Cromoglicate Efficacy and Safety in Symptomatic Management of Fatigue in Multiple Sclerosis: A Randomized, Placebo-Controlled Trial
- Evaluation of Ofatumumab Efficacy and Patient-Reported Outcomes in Relapsing Multiple Sclerosis Patients Transitioning from Fumarate-Based Therapies or Fingolimod
Data & Insights
Has run more than one trial at 224 of 421 partner sites.
Specializations
Neuroimmunology and multiple sclerosis
Clinical research in multiple sclerosis, including relapsing and progressive forms, alongside studies in clinically isolated syndrome and other autoimmune neurological diseases.
- Relapsing multiple sclerosis
- Progressive multiple sclerosis
- Myelin oligodendrocyte glycoprotein antibody-associated disease
- Chronic inflammatory demyelinating polyneuropathy
Interest also extends to therapies aimed at controlling immune-mediated neurological disability and maintaining long-term function.
Epilepsy, seizure disorders, and migraine
Work in epilepsy covers focal and generalized seizure syndromes, refractory seizure control, and related neurological symptom burden.
- Focal onset seizures
- Primary generalized tonic-clonic seizures
- Refractory status epilepticus
- Migraine
Therapeutic interest includes neurological symptom prevention and treatment strategies for both chronic and acute seizure-related conditions.
Neurodegeneration and cognitive disorders
Research activity includes Alzheimer's disease, Parkinson's disease, and associated neuropsychiatric manifestations, with attention to cognition, behavior, and disease progression.
- Alzheimer's disease
- Psychosis associated with Alzheimer's disease
- Early Parkinson's disease
- Cognitive impairment
This therapeutic area also includes interventions for agitation, anhedonia, and other symptoms linked to degenerative brain disease.
Breast cancer and other solid tumors
The oncology portfolio is centered on breast cancer, particularly hormone receptor-positive, HER2-negative, and triple-negative breast cancer, with additional involvement in lung cancer, renal cell carcinoma, urothelial carcinoma, and gynecologic malignancies.
- Advanced breast cancer
- Non-small cell lung cancer
- Renal cell carcinoma
- Urothelial carcinoma
Therapeutic focus includes targeted and immuno-oncology approaches across advanced, metastatic, and early-stage solid tumors.
Cardiovascular, renal, and systemic inflammatory disease
Additional research spans atherosclerotic cardiovascular disease, heart failure, stroke, hypertension, and thromboembolic disease, together with kidney disease and immune-mediated renal disorders.
- Acute coronary syndrome
- Acute ischemic stroke
- Chronic kidney disease
- IgA nephropathy
Her therapeutic interests also include inflammatory and autoimmune conditions such as systemic lupus erythematosus, psoriasis, and atopic dermatitis.
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