Cédric C.
- Country
- France
- Department
- Radiotherapy
Research Overview
- Phase II-III Multicentric Trial on Tailored Management of Locally-Advanced Rectal Carcinoma with Irinotecan Hydrochloride and Drug Combination
- Phase III Randomized Trial of Avelumab, Cetuximab, and Radiotherapy Versus Standard Care in Locally Advanced Squamous Cell Carcinoma of the Head and Neck
- Neoadjuvant Dostarlimab and Short-Course Radiotherapy in Microsatellite Unstable or Mismatch Repair-Deficient Locally Advanced Rectal Cancer
Data & Insights
Has run more than one trial at 35 of 101 partner sites.
Specializations
Radiotherapy and Head and Neck Oncology
Clinical research activity is centered on radiotherapy for head and neck cancers, including sinus tumors, salivary gland carcinomas, and other locally advanced or recurrent head and neck squamous cell carcinoma.
- Resected and non-operable tumors of the sinuses or salivary glands
- Advanced head and neck squamous cell carcinoma
- Cutaneous squamous cell carcinoma
The therapeutic focus also includes postoperative and definitive treatment strategies in anatomically complex head and neck malignancies.
Thoracic Oncology
A major area of interest is non-small cell lung cancer, with research spanning locally advanced, metastatic, and resected disease, as well as biomarker-defined subgroups such as EGFR-altered, ALK-wild type, and KRAS G12C-mutated tumors.
- Locally advanced and metastatic NSCLC
- Resected early-stage NSCLC
- Small cell lung cancer
Work in this domain reflects a strong therapeutic emphasis on precision-driven management of lung cancer and related thoracic malignancies.
Breast and Gynecologic Cancers
Research involvement extends across breast cancer and gynecologic oncology, including hormone receptor-defined disease, HER2-positive and HER2-negative breast cancer, as well as endometrial, ovarian, cervical, and vulvar malignancies.
- Metastatic and early breast cancer
- Endometrial and ovarian cancer
- Cervical and vulvar squamous cell carcinoma
The portfolio also includes biomarker-defined tumors such as HR-positive, HER2-low, and mismatch repair-deficient cancers.
Gastrointestinal and Hepatobiliary Oncology
Another prominent field is gastrointestinal cancer, with activity in colorectal cancer, gastric and gastroesophageal junction adenocarcinoma, pancreatic adenocarcinoma, esophageal carcinoma, and hepatocellular carcinoma.
- Colorectal and rectal cancer
- Gastric, gastroesophageal, and esophageal cancer
- Hepatocellular and biliary tract cancer
Therapeutic interests also cover biliary tract cancer, neuroendocrine tumors, and other advanced solid tumors of the digestive system.
Genitourinary Cancer and Sarcoma
Clinical research also includes prostate cancer, renal cell carcinoma, and urothelial carcinoma, alongside a substantial interest in soft-tissue sarcoma and bone sarcoma.
- Metastatic and castration-resistant prostate cancer
- Renal cell and urothelial carcinoma
- Soft-tissue and bone sarcomas
Additional activity includes rare and aggressive tumor types such as melanoma, glioblastoma, and selected hematologic malignancies.
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