Cécile T.
- Country
- France
- Department
- Service Hématologie
Research Overview
- Phase 2 Study on Zanubrutinib and BGB-11417 Efficacy and Tolerance in Previously Treated Waldenström Macroglobulinemia Patients
- Phase 3 Randomized Study of Pirtobrutinib, Venetoclax, and Rituximab in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
- Phase 3 Study of Lisaftoclax (APG-2575) and Acalabrutinib in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Patients
Data & Insights
Has run more than one trial at 70 of 260 partner sites.
Specializations
Hematologic malignancies
Clinical research is centered on adult and pediatric leukemias, lymphomas, myelodysplastic syndromes, and multiple myeloma, with attention to relapsed, refractory, and newly diagnosed disease settings.
- Acute lymphoblastic leukemia
- Acute myeloid leukemia
- Diffuse large B-cell lymphoma
- Multiple myeloma
- Myelodysplastic syndrome
Interest also extends to myelofibrosis, chronic lymphocytic leukemia, and other blood cancers managed through the Hématologie department at Centre Hospitalier Universitaire De Poitiers.
Solid tumors and thoracic oncology
The investigator is involved in a broad range of solid tumor studies, especially breast cancer, colorectal cancer, gastric cancer, and pancreatic cancer, along with difficult-to-treat advanced and metastatic presentations.
- Non-small cell lung cancer
- Breast cancer
- Colorectal cancer
- Gastric and gastroesophageal junction cancer
- Pancreatic adenocarcinoma
Additional activity includes head and neck cancer, renal cell carcinoma, urothelial carcinoma, and sarcoma, reflecting a strong focus on oncologic innovation across multiple tumor types.
Plasma cell disorders and amyloidosis
Research activity includes AL amyloidosis, transthyretin amyloid cardiomyopathy, and related plasma cell dyscrasia conditions, with emphasis on severe systemic manifestations and hematologic overlap.
- Light chain amyloidosis
- Transthyretin amyloid cardiomyopathy
- Waldenström macroglobulinemia
- Plasma cell myeloma
- Monoclonal gammopathy
This domain also covers relapsed multiple myeloma and high-risk smoldering myeloma, supporting therapeutic development in rare and advanced hematologic disease.
Cardiovascular and thromboembolic disease
The investigator contributes to studies in acute myocardial infarction, stroke, atrial fibrillation, and broader atherosclerotic cardiovascular disease, including prevention and post-event management.
- Heart failure
- Ischemic stroke
- Acute coronary syndrome
- Venous thromboembolism
- Pulmonary arterial hypertension
Work in this area also includes valvular heart disease, hypertension, and cardiovascular risk reduction, linking hematology practice with cardiovascular outcomes.
Autoimmune, inflammatory, and transplant-related conditions
Clinical involvement extends to systemic lupus erythematosus, rheumatoid arthritis, giant cell arteritis, and other immune-mediated disorders, together with vasculitis and inflammatory syndromes.
- Systemic lupus erythematosus
- Rheumatoid arthritis
- Giant cell arteritis
- ANCA-associated vasculitis
- Kidney transplantation
Research also includes graft-versus-host disease, immune thrombocytopenia, and selected infectious complications in critically ill or immunocompromised patients.
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