Cécile D. M.
- Country
- France
- Department
- Service d’Oncologie
Research Overview
- IFCT-2201 ADAPTABLE A non-comparative randomized phase II trial evaluating the combination of paclitaxel-bevacizumab ± atezolizumab in patients with advanced non-squamous NSCLC progressing after immunotherapy and chemotherapy
- Randomized Phase II-III Trial of Maintenance Pembrolizumab ± Pemetrexed Versus Observation ± Pemetrexed in Stage IV Non-Small Cell Lung Cancer Post-Induction Therapy
- A Phase III Double-Blind, Placebo-Controlled Study of Adjuvant Durvalumab in Resected Stage IB-IIIA Non-Small Cell Lung Cancer with PD-L1 Expression ≥25%
Data & Insights
Has run more than one trial at 51 of 150 partner sites.
Specializations
Hematologic Oncology
The investigator concentrates on malignant blood disorders, including Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myeloid Leukemia, and Multiple Myeloma, addressing both newly diagnosed and relapsed disease states.
- Acute Myeloid Leukemia
- Acute Lymphoblastic Leukemia
- Chronic Myeloid Leukemia
- Multiple Myeloma
- Myelodysplastic Syndromes
Therapeutic strategies span targeted agents, immunotherapies, and stem cell transplantation to improve survival and disease control.
Solid Tumor Oncology
Research efforts target a broad range of solid cancers such as Non‑Small Cell Lung Cancer, Breast Cancer, Colorectal Cancer, Prostate Cancer, and Ovarian Cancer, with emphasis on advanced and metastatic disease.
- Non‑Small Cell Lung Cancer
- Breast Cancer
- Colorectal Cancer
- Prostate Cancer
- Ovarian Cancer
Focus includes immuno‑oncology, targeted kinase inhibition, and combination chemotherapy regimens.
Cardiovascular Medicine
The investigator is engaged in studies of acute and chronic heart conditions, covering Acute Myocardial Infarction, Heart Failure, Stroke, and Venous Thromboembolism, as well as preventive lipid‑lowering therapies.
- Acute Myocardial Infarction
- Heart Failure
- Stroke
- Venous Thromboembolism
- Lipid‑Lowering Therapy
Therapeutic aims include reducing mortality, improving cardiac function, and preventing recurrent vascular events.
Pulmonary & Respiratory Diseases
Clinical work addresses chronic and acute airway disorders, notably Chronic Obstructive Pulmonary Disease, Severe Asthma, Bronchiectasis, and Respiratory Syncytial Virus infection in high‑risk populations.
- Chronic Obstructive Pulmonary Disease
- Severe Asthma
- Bronchiectasis
- Respiratory Syncytial Virus
- Influenza‑Related Acute Respiratory Failure
Interventions explore anti‑inflammatory agents, antiviral prophylaxis, and supportive ventilation strategies.
Autoimmune & Inflammatory Disorders
Investigations include systemic immune conditions such as Rheumatoid Arthritis, ANCA‑Associated Vasculitis, Giant Cell Arteritis, and Familial Mediterranean Fever, focusing on disease modulation and flare prevention.
- Rheumatoid Arthritis
- ANCA‑Associated Vasculitis
- Giant Cell Arteritis
- Familial Mediterranean Fever
- Sarcoidosis
Therapeutic approaches involve biologics, cytokine inhibitors, and personalized immunomodulation.
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