Cathrine A.
- Country
- Norway
- Department
- Drammen Hospital, Vestre Viken, Revmatologi
Research Overview
- Phase 4 Randomized Trial of Maintenance vs Tapered TNF‑α Inhibitor (adalimumab, etanercept, golimumab) Monotherapy in Juvenile Idiopathic Arthritis with Inactive Disease
- Evaluation of Methotrexate and Tumor Necrosis Factor Inhibitor Withdrawal Strategies in Juvenile Idiopathic Arthritis Remission: A Randomized Multicenter Trial
Data & Insights
Has run more than one trial at 2 of 8 partner sites.
Specializations
Oncology
The investigator engages in therapeutic research targeting a broad spectrum of solid tumours, with particular emphasis on molecularly defined subtypes.
- non‑small cell lung cancer with KRAS or EGFR mutations
- HER2‑positive breast cancer and triple‑negative disease
- advanced melanoma treated with immunotherapy
- small‑cell lung cancer extensive stage
- acute myeloid leukaemia with NPM1 mutation
These efforts aim to integrate targeted agents and immune‑modulating strategies to improve survival outcomes.
Autoimmune & Inflammatory Disorders
In the realm of immune‑mediated disease, the investigator focuses on precision therapies for chronic inflammatory conditions.
- moderately to severely active Crohn's disease
- juvenile idiopathic arthritis
- relapsing‑remitting multiple sclerosis
- rheumatoid arthritis phenotypes
- ulcerative colitis treatment pathways
Therapeutic goals include achieving durable remission while minimizing systemic toxicity.
Cardiovascular & Metabolic Medicine
The investigator contributes to studies addressing major cardiometabolic risk factors and heart failure management.
- chronic heart failure with iron deficiency
- type 2 diabetes combined with hypertension
- obesity and its cardiovascular sequelae
- atherosclerotic cardiovascular disease in end‑stage kidney disease
- post‑hip fracture bone health
Research seeks to refine risk reduction strategies and evaluate novel metabolic agents.
Neurology & Neurodegenerative Diseases
Neurological investigations centre on disease‑modifying approaches for progressive disorders.
- amyotrophic lateral sclerosis
- acute ischemic stroke with rapid thrombolysis
- multiple sclerosis targeting viral contributors
- neuroinflammation in autoimmune contexts
- neuroprotective agents in early disease stages
Efforts aim to slow disease progression and improve functional outcomes.
Respiratory & Infectious Diseases
Research in pulmonary and infectious fields addresses both chronic and acute respiratory conditions.
- chronic obstructive pulmonary disease
- viral respiratory tract infections including COVID‑19
- sepsis management strategies
- antiviral combination therapy for immunocompromised patients
- antibiotic stewardship in viral airway infections
The focus is on optimizing therapeutic regimens to reduce morbidity and mortality.
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