Carsten D.
- Country
- Denmark
- Department
- N/A
Research Overview
- Efficacy and safety of zenagamtide once-weekly subcutaneous treatment for obesity in adults versus placebo
- Phase III Randomized, Double‑Blind, Parallel‑Group Study of Elecoglipron Added to Dapagliflozin in Adults with Type 2 Diabetes Mellitus and Impaired Renal Function
- Phase III Randomized Double‑Blind Study of Elecoglipron Plus Dapagliflozin Versus Elecoglipron or Dapagliflozin Monotherapy in Adults with Type 2 Diabetes Mellitus
Data & Insights
Has run more than one trial at 56 of 334 partner sites.
Specializations
Oncology
Clinical research activity includes a broad oncology portfolio spanning gastrointestinal cancers, lung cancer, melanoma, breast cancer, genitourinary malignancies, and gynecological cancers, with particular attention to advanced and metastatic disease.
- Solid tumors
- Immunotherapy
- Targeted cancer treatment
- Perioperative and adjuvant oncology
Therapeutic interests also extend to biomarker-defined cancers, including MSI-H, dMMR, TMB-H, and PD-L1-associated disease, as well as tumor types such as pancreatic cancer, bladder cancer, renal cell carcinoma, and head and neck squamous cell carcinoma.
Inflammatory and autoimmune disease
Research involvement covers chronic immune-mediated conditions, especially Crohn’s disease, ulcerative colitis, and related inflammatory bowel disease phenotypes, alongside rheumatoid arthritis, psoriasis, and atopic dermatitis.
- Inflammatory bowel disease
- Immune modulation
- Autoimmune skin disease
- Rheumatologic inflammation
Additional therapeutic interests include immune checkpoint inhibitor-related colitis, hidradenitis suppurativa, and other persistent inflammatory disorders requiring long-term disease control.
Cardiovascular and metabolic medicine
The investigator is active in studies of heart failure, atrial fibrillation, ischemic stroke prevention, coronary artery disease, and atherosclerotic cardiovascular disease, with a strong emphasis on risk reduction in complex cardiovascular populations.
- Heart failure
- Thromboembolic prevention
- Cardiovascular risk
- Lipid disorders
Research also includes hypertension, dyslipidemia, obesity, diabetes mellitus, and related cardiometabolic conditions, including patients with chronic kidney disease or dialysis-dependent disease.
Hepatology and nephrology
Clinical interests extend to liver disease, including alcohol-related liver disease, cirrhosis, portal hypertension, non-alcoholic steatohepatitis, and alpha-1 antitrypsin deficiency-associated liver disease, as well as renal disorders such as IgA nephropathy and idiopathic membranous nephropathy.
- Chronic liver disease
- Fibrosis
- Proteinuric kidney disease
- Renal replacement therapy
Therapeutic focus also includes adynamic bone disorder in chronic kidney disease and treatment strategies for complications of advanced hepatic and renal dysfunction.
Neurology, respiratory disease, and supportive care
Research activity includes migraine, Tourette’s disorder, multiple sclerosis, and other neurological conditions, together with asthma, chronic obstructive pulmonary disease, and bronchiectasis.
- Neurological disorders
- Airway disease
- Symptom control
- Perioperative and inpatient care
Additional areas include pain management, postoperative infection prevention, and acute care conditions such as sepsis, cardiac arrest, and pulmonary edema.
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