Carolin G. O. M.
- Country
- Germany
- Department
- Studienzentrum der Lungenklinik
Research Overview
- Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Patients With Previously Treated TROP2-Positive Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
- Tarlatamab plus Durvalumab versus Durvalumab Alone in Patients with Extensive-Stage Small Cell Lung Cancer Following Platinum-Etoposide Therapy
- Phase 3 Study of Pumitamig Versus Pembrolizumab in Previously Untreated Advanced Non-Small Cell Lung Cancer with PD-L1 ≥50%
Data & Insights
Has run more than one trial at 193 of 443 partner sites.
Specializations
Advanced Lung Cancer Research
This investigator specializes in treating non-small cell lung cancer (NSCLC), with particular emphasis on both squamous and non-squamous variants. Their research encompasses metastatic disease states and various genetic expressions including PD-L1, HER2 mutations, and EGFR mutations.
- Metastatic squamous and non-squamous NSCLC
- TTF-1 negative lung adenocarcinoma
- Locally advanced unresectable NSCLC
Immunotherapy Applications
The investigator focuses on innovative immunotherapeutic approaches in lung cancer treatment, including studies with checkpoint inhibitors and novel combination therapies. Their work includes evaluation of treatments such as atezolizumab, pembrolizumab, and emerging immunotherapy agents.
- PD-L1 expressing tumors
- Post-immunotherapy progression
- Combination immunotherapy strategies
Targeted Therapeutic Development
The investigator explores targeted therapy approaches for specific genetic mutations in lung cancer. Their research includes evaluation of novel agents targeting HER2 mutations and investigation of EGFR-targeted therapies in combination with other treatment modalities.
- EGFR mutation-positive treatments
- HER2-directed therapies
- Combination treatment strategies
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