Silverio P.
- Country
- Italy
- Department
- U.O.C. Oncologia Medica ed Ematologia, Dipartimento di Medicina di Precisione
Research Overview
- Effisayil® REP: An open-label, multicenter, single-arm, post-marketing trial (in select countries) to evaluate efficacy and safety and the impact of immunogenicity on efficacy, safety, and pharmacokinetics of spesolimab i.v. in treatment of patients with Generalized Pustular Psoriasis (GPP) presenting with a recurrent flare following their initial GPP flare treatment with spesolimab i.v.
- Dose-Escalation and Dose-Finding Study of (S)-4,5-Dihydro-2-[2-Hydroxy-4-(3,6-Dioxaheptyloxy)phenyl]-4-Methyl-4-Thiazolecarboxylic Acid in Transfusion-Dependent α- or β-Thalassemia
- Efficacy and Safety Evaluation of Selumetinib in Adults with Neurofibromatosis Type 1 and Symptomatic, Inoperable Plexiform Neurofibromas
Data & Insights
Has run more than one trial at 32 of 94 partner sites.
Specializations
Hematological Disorders
The investigator specializes in treating various forms of thalassemia, including both alpha and beta variants, with particular focus on transfusion-dependent cases. Their research encompasses innovative therapeutic approaches for managing hemoglobinopathies and related blood disorders.
- Alpha-thalassemia management
- Beta-thalassemia treatment
- Transfusion dependency optimization
Sickle Cell Disease
Extensive work in sickle cell disease treatment, focusing on developing therapeutic solutions for managing vaso-occlusive episodes and related complications. The investigator studies novel approaches to address anemia in SCD patients.
- Pain crisis management
- Anemia treatment
- Disease modification therapies
Oncology and Rare Diseases
The investigator conducts research in neuroblastoma treatment strategies and management of neurofibromatosis type 1. Their work includes evaluation of novel therapeutic approaches for inoperable plexiform neurofibromas.
- High-risk neuroblastoma treatment
- Neurofibromatosis management
- Rare disease therapeutics
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