Carlotta C.
- Country
- Italy
- Department
- Dip.to di Scienze Pediatriche e dell'Adolescenza
Research Overview
Data & Insights
Has run more than one trial at 0 of 15 partner sites.
Specializations
Metabolic Liver Disease
Investigator Covizzi concentrates on liver conditions linked to metabolic dysfunction, emphasizing the progressive form of fatty liver disease and its complications.
- Non‑Alcoholic Steatohepatitis (NASH)
- Metabolic Dysfunction‑Associated Steatohepatitis (MASH)
- Cirrhosis secondary to fatty liver disease
- Hepatocellular carcinoma arising from chronic liver injury
- Obesity‑related liver inflammation
Research is conducted at the Azienda Ospedaliera Universitaria Città della Salute e della Scienza di Torino, integrating pediatric metabolic insights with adult hepatology.
Pediatric Oncology
The investigator engages in clinical studies of malignant solid and hematologic tumors affecting children and adolescents, spanning rare and common pediatric cancers.
- Acute Lymphoblastic Leukemia (ALL)
- Acute Myeloid Leukemia (AML)
- Neuroblastoma and related high‑risk solid tumors
- Medulloblastoma and other embryonal brain tumors
- Rhabdomyosarcoma (RMS)
Efforts focus on improving survival and reducing long‑term toxicity through targeted therapies and multimodal regimens.
Hematology and Stem Cell Transplantation
Covizzi’s work includes disorders of blood formation and the application of hematopoietic stem cell transplantation in pediatric settings.
- Hematopoietic stem cell transplantation
- Graft‑Versus‑Host Disease (GVHD)
- Chronic Lymphocytic Leukemia (CLL) in young patients
- Myelodysplastic Syndromes (MDS)
- Thalassemia and other hemoglobinopathies
The program aims to refine conditioning protocols and post‑transplant immune management for pediatric recipients.
Cardiovascular and Metabolic Risk
Research addresses early‑onset cardiovascular disease and its metabolic precursors, reflecting the interplay between pediatric risk factors and adult outcomes.
- Atherosclerotic Cardiovascular Disease (ASCVD)
- Atrial Fibrillation in young adults
- Hypertension resistant to standard therapy
- Type 2 Diabetes Mellitus and its pediatric manifestations
- Obesity‑related metabolic syndrome
Studies explore preventive strategies and novel anti‑inflammatory approaches to mitigate long‑term cardiovascular events.
Neurodegenerative and Neurodevelopmental Disorders
The investigator participates in trials targeting progressive neurological conditions that begin in childhood or have early‑onset phenotypes.
- Alzheimer’s Disease and related cognitive decline
- Amyotrophic Lateral Sclerosis (ALS)
- Multiple Sclerosis (MS) subtypes
- Spinal Muscular Atrophy (SMA)
- Juvenile Idiopathic Arthritis with neurological involvement
Efforts focus on disease‑modifying agents and biomarkers to monitor disease progression in pediatric populations.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.