Carlos G.
- Country
- Belgium
- Department
- Hematologie
Research Overview
- Evaluation of Blinatumomab, Isatuximab, and Ponatinib in Frontline Therapy for Adults with Acute Lymphoblastic Leukemia and T-Lymphoblastic Lymphoma
- Blinatumomab and Combination Therapy Versus Standard of Care in Older Adults With Newly Diagnosed Philadelphia-Negative B-Cell Precursor Acute Lymphoblastic Leukemia
- Phase 1/2 Study of Subcutaneous Blinatumomab in Adults and Adolescents with Relapsed/Refractory or MRD+ B-cell Precursor Acute Lymphoblastic Leukemia
Data & Insights
Has run more than one trial at 139 of 260 partner sites.
Specializations
Acute Leukemia Research
This investigator specializes in studying various forms of acute leukemia, with particular emphasis on both myeloid and lymphoblastic variants. Their research encompasses relapsed and refractory acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) in adult patients.
- IDH1 mutation-positive AML treatment approaches
- RARA-positive leukemia interventions
- NPM1-mutated AML therapies
The investigator's work includes innovative approaches such as dendritic cell vaccination and targeted molecular therapies.
Myelodysplastic Syndromes
A significant focus of research lies in treating higher-risk myelodysplastic syndrome (MDS), investigating novel therapeutic combinations and approaches for patient care.
- RARA-positive MDS treatment strategies
- Venetoclax combination therapies
- Azacitidine-based treatment protocols
The research extends to studying treatment-naïve higher-risk MDS populations and novel therapeutic combinations.
Transplantation Medicine
The investigator conducts research in allogeneic hematopoietic stem cell transplantation, exploring various conditioning regimens and treatment protocols.
- Reduced-intensity conditioning protocols
- HLA-matched donor transplantation
- Post-transplant therapeutic strategies
Their work encompasses transplantation approaches for various hematological malignancies, including both myeloid and lymphoid conditions.
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