Bram V.
- Country
- Belgium
- Department
- Department of Gastroenterology and Hepatology
Research Overview
- A Randomized, Open-label, Phase 2 study of Botensilimab (AGEN1181) as Monotherapy and in Combination with Balstilimab (AGEN2034) or Investigator’s Choice Standard of Care (Regorafenib or Trifluridine and Tipiracil) for the Treatment of Refractory Metastatic Colorectal Cancer
- A Phase 1 Study of Afimkibart Effects on Cytochrome P450-Mediated Drug Metabolism in Patients With Active Ulcerative Colitis
- Phase 3b, Randomized, Open‑Label, Active‑Controlled Trial Comparing Guselkumab Versus Risankizumab for Efficacy and Safety in Moderately to Severely Active Crohn’s Disease
Data & Insights
Has run more than one trial at 287 of 488 partner sites.
Specializations
Inflammatory Bowel Disease Management
Specializes in treating inflammatory bowel diseases, with particular focus on both ulcerative colitis and Crohn's disease across various severity levels.
- Moderate to Severe Ulcerative Colitis
- Acute Severe Ulcerative Colitis
- Moderately to Severely Active Crohn's Disease
Explores novel therapeutic approaches for inflammatory bowel conditions through clinical research.
Advanced Treatment Modalities
Investigates innovative therapeutic agents and treatment strategies for gastrointestinal disorders, including precision dosing approaches and targeted therapies.
- Novel Oral Therapeutics
- Model-Informed Precision Dosing
- Transmural Healing Approaches
Focuses on developing personalized treatment strategies for optimal patient outcomes.
Specialized Clinical Conditions
Addresses complex gastrointestinal conditions requiring specialized care, including management of patients with ileostomy and steroid-refractory conditions.
- Ileal Crohn's Disease with Ileostomy
- Steroid-Refractory Cases
- Biomarker-Guided Treatment
Employs advanced therapeutic monitoring and disease assessment techniques.
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