Bozena C. S.
- Country
- Poland
- Department
- Clinical Trials Unit
Research Overview
- A Phase 3 Randomized Open-Label Study of Sacituzumab Govitecan Versus Physician's Choice in Recurrent or Persistent Endometrial Cancer Post-Chemotherapy and Immunotherapy
- A Phase 3, Randomized, Open-label, Study of Subcutaneous Nivolumab + Relatlimab Fixed-dose Combination versus Intravenous Nivolumab + Relatlimab Fixed-dose Combination in Participants with Previously Untreated Metastatic or Unresectable Melanoma
- A Phase 3, Randomized, Double-blind, Active-Comparator-Controlled Clinical Study of Adjuvant MK-7684A (Vibostolimab with Pembrolizumab) Versus Adjuvant Pembrolizumab in Participants with High-risk Stage II-IV Melanoma (KEYVIBE-010)
Data & Insights
Has run more than one trial at 350 of 602 partner sites.
Specializations
Oncology and Hematologic Malignancies
Clinical research activity includes a broad range of solid tumors and blood cancers, with particular involvement in non-small cell lung cancer, breast cancer, urothelial carcinoma, renal cell carcinoma, hepatocellular carcinoma, and melanoma. Hematology-focused work spans diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, chronic lymphocytic leukemia, multiple myeloma, and acute myeloid leukemia.
- Advanced solid tumors
- Relapsed or refractory lymphomas
- Myeloid and plasma cell disorders
The portfolio also includes studies in head and neck squamous cell carcinoma, ovarian cancer, cervical cancer, and other metastatic malignancies.
Autoimmune and Inflammatory Disease
Research interests extend across immune-mediated disorders such as rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis, systemic lupus erythematosus, Sjögren’s syndrome, ulcerative colitis, and Crohn’s disease. Additional activity includes atopic dermatitis, hidradenitis suppurativa, psoriasis, and chronic spontaneous urticaria.
- Inflammatory arthritis
- Connective tissue diseases
- Immune-mediated skin and bowel disease
These studies reflect a strong therapeutic focus on chronic immune dysregulation and inflammatory burden.
Respiratory and Allergic Disorders
Clinical trial involvement includes chronic obstructive pulmonary disease, asthma, allergic rhinitis, rhinoconjunctivitis, and chronic cough. The respiratory portfolio also covers bronchiectasis and respiratory syncytial virus prevention and infection-related conditions.
- COPD and asthma
- Allergic airway disease
- Respiratory infection prevention
This area includes treatment development for persistent airway inflammation and symptom control in both allergic and obstructive lung disease.
Cardiometabolic and Renal Medicine
Therapeutic interests also include atherosclerotic cardiovascular disease, heart failure, atrial fibrillation, hypertension, hypertriglyceridemia, obesity, and type 2 diabetes. Renal-focused studies involve chronic kidney disease and IgA nephropathy, alongside metabolic liver disease such as MASH and NASH.
- Cardiovascular risk reduction
- Diabetes and obesity
- Kidney and metabolic liver disease
The portfolio reflects ongoing engagement in prevention and treatment of cardiometabolic complications and organ damage.
Neurology, Pain, and Dermatologic Conditions
Additional research activity covers multiple sclerosis, migraine, epilepsy, Parkinson’s disease, and early Alzheimer’s disease. Pain-related work includes diabetic peripheral neuropathic pain, knee osteoarthritis pain, and chronic low back pain, while dermatologic studies include prurigo nodularis, alopecia areata, and prurigo nodularis.
- Neuroinflammatory disease
- Chronic pain syndromes
- Dermatologic symptom burden
These trial areas align with therapies targeting long-standing neurologic symptoms, pain control, and inflammatory skin disease.
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