Björn T.
- Country
- Germany
- Department
- Klinik für Nephrologie und Rheumatologie
Research Overview
- Phase III Randomized Double‑Blind Placebo‑Controlled Trial of Elecoglipron (AZD5004) on Renal Decline and Mortality in Adults with Chronic Kidney Disease
- Phase 2, Randomized, Double-Blind, Placebo-controlled, Parallel-Group, Multicenter Study to Evaluate the Safety and Efficacy of Tarperprumig in Adult Participants with Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Data & Insights
Has run more than one trial at 7 of 230 partner sites.
Specializations
Renal Medicine
Focused on disorders of kidney function, ranging from Acute kidney injury to progressive Chronic kidney disease and hereditary nephropathies.
- Acute kidney injury
- Chronic kidney disease
- Alport syndrome
- Primary steroid‑resistant focal segmental glomerulosclerosis
- Renal involvement in ANCA‑associated vasculitis
Efforts aim to translate renal pathophysiology into targeted therapeutic interventions.
Autoimmune and Inflammatory Rheumatology
Investigation of systemic immune‑mediated diseases, including muscular and connective‑tissue disorders.
- Myasthenia gravis
- Anti‑synthetase syndrome
- Immune‑mediated necrotizing myopathy
- Dermatomyositis
- ANCA‑associated vasculitis
Research integrates serologic biomarkers with clinical phenotyping to refine disease‑specific therapies.
Hematologic Malignancies and Plasma Cell Disorders
Targeted studies on blood‑borne cancers and related disorders.
- Acute myeloid leukemia
- Acute lymphoblastic leukemia
- Diffuse large B‑cell lymphoma
- Multiple myeloma
- Chronic myelomonocytic leukemia
Efforts emphasize molecular classification and novel immunotherapeutic approaches.
Neurology and Neurodegeneration
Exploration of neuro‑inflammatory and degenerative conditions affecting the central nervous system.
- Multiple sclerosis
- Amyotrophic lateral sclerosis
- Alzheimer’s disease
- Parkinson’s disease
- Vascular dementia
Investigations combine neuroimaging, fluid biomarkers, and therapeutic modulation of neuroinflammation.
Oncology and Solid Tumor Therapeutics
Broad engagement with malignant solid tumors across organ systems.
- Non‑small cell lung cancer
- Breast cancer
- Colorectal cancer
- Hepatocellular carcinoma
- Pancreatic ductal adenocarcinoma
Research prioritizes molecularly driven treatment strategies and resistance mechanisms.
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