Bettina S.
- Country
- Germany
- Department
- #40683: Klinik für Neurologie
Research Overview
- A Multicenter, Open-label, Long-term, Safety, Tolerability, and Efficacy Study of XEN1101 in Subjects Diagnosed With Epilepsy (X-TOLE4)
- Evaluation of Long-Term Safety and Tolerability of Staccato Alprazolam in Patients Aged 12 and Older with Stereotypical Prolonged Seizures
- Comparative Effectiveness of Levetiracetam and Valproate Semisodium in Benzodiazepine-Resistant Status Epilepticus in Patients Aged 65 and Older
Data & Insights
Has run more than one trial at 132 of 356 partner sites.
Specializations
Stroke and Acute Cerebrovascular Disease
Clinical research activity includes acute ischemic stroke, high-risk transient ischemic attack, and secondary prevention after recent cerebrovascular events, with additional interest in stroke patients with atrial fibrillation.
- Ischemic stroke prevention
- Transient ischemic attack
- Cardioembolic and non-cardioembolic risk reduction
Work in this area is centered in the Stroke Unit and linked to antithrombotic strategies for preventing recurrent vascular events.
Epilepsy and Seizure Disorders
The investigator is involved in studies across focal-onset seizures, primary generalized tonic-clonic seizures, idiopathic generalized epilepsy, and status epilepticus, including refractory seizure presentations in older adults.
- Focal epilepsy
- Generalized seizure syndromes
- Established status epilepticus
This research domain reflects a strong therapeutic focus on seizure control and acute management of severe epileptic emergencies within the Center for Epilepsy.
Lung Cancer and Thoracic Oncology
Research involvement spans non-small cell lung cancer, small cell lung cancer, and locally advanced or metastatic lung malignancies, with emphasis on perioperative, adjuvant, and advanced-disease treatment approaches.
- Non-small cell lung cancer
- Small cell lung cancer
- PD-L1-directed treatment strategies
The therapeutic landscape also includes progressive pulmonary fibrosis and idiopathic pulmonary fibrosis, extending interest into chronic lung disease.
Hematologic Malignancies
The investigator contributes to clinical research in lymphoma, multiple myeloma, acute myeloid leukemia, and related B-cell neoplasms, covering both newly diagnosed and relapsed or refractory disease settings.
- Diffuse large B-cell lymphoma
- Follicular lymphoma
- Multiple myeloma
This area also includes interest in Waldenström’s macroglobulinemia and other aggressive hematologic cancers treated with modern immunologic and targeted approaches.
Solid Tumors and Targeted Oncology
Additional research spans breast cancer, prostate cancer, bladder cancer, head and neck cancer, and gastrointestinal malignancies, with participation in studies of immunotherapy, antibody-based therapy, and radioligand treatment.
- Metastatic breast cancer
- Prostate cancer
- Head and neck squamous cell carcinoma
Interest also extends to colorectal cancer, gastric cancer, and melanoma, reflecting broad involvement in contemporary solid-tumor therapeutics.
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