BERTA L.
- Country
- Spain
- Department
- ONCOLOGY
Research Overview
Data & Insights
Has run more than one trial at 0 of 10 partner sites.
Specializations
Hormone Receptor‑Positive Breast Cancer
The investigator concentrates on advanced and metastatic HR‑positive, HER2‑negative breast cancer, addressing endocrine resistance and optimizing adjuvant strategies.
- Endocrine therapy resistance
- CDK4/6 inhibitor combinations
- Adjuvant therapy in early‑stage HR+ disease
Research aims to improve outcomes for patients with hormone‑driven disease across disease stages.
HER2‑Positive and Triple‑Negative Breast Cancer
Focused on biologically aggressive subtypes, including HER2‑positive and triple‑negative breast cancer, the work explores novel antibody‑drug conjugates and immunotherapeutic approaches.
- HER2‑targeted ADCs
- HER2‑low therapeutic strategies
- Immunotherapy in triple‑negative disease
Efforts target unmet needs in high‑risk breast cancer phenotypes.
Hematologic Malignancies
Active in the study of blood cancers, the investigator addresses both acute and chronic entities, spanning myeloid and lymphoid lineages.
- Acute Myeloid Leukemia
- Myelodysplastic Syndromes
- Chronic Lymphocytic Leukemia
- Multiple Myeloma
- B‑cell Lymphomas
Research supports novel therapeutic options for patients with high‑risk hematologic disease.
Targeted Therapy in Advanced Solid Tumors
Investigations include molecularly defined cancers such as non‑small cell lung cancer, colorectal, gastric, pancreatic and renal cell carcinomas.
- KRAS G12C mutation
- EGFR‑mutated NSCLC
- ALK‑positive lung cancer
- HER2‑mutated solid tumors
- FGFR2b‑positive gastric cancer
Efforts aim to match targeted agents with specific oncogenic drivers.
Immuno‑Oncology and Cellular Therapies
Broad engagement with immune‑based strategies, including checkpoint inhibition and engineered cell therapies across malignancies.
- PD‑1/PD‑L1 blockade
- CAR‑T cell therapy
- Lymphoma immunotherapy
- Immune‑modulating agents in solid tumors
Work focuses on enhancing antitumor immunity and expanding cellular platforms.
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