Bernhard B.
- Country
- Germany
- Department
- Klinik für Psychische Gesundheit
Research Overview
- Phase 2b Randomized, Double-Blind, Placebo-Controlled Trial Evaluating Mebufotenin (GH001) Efficacy and Safety in Treatment-Resistant Depression Patients
- Evaluation of Intensified Pharmacological Treatment with Esketamine for Major Depressive Disorder in Patients with First-Line Treatment Failure
- Evaluation of Intensified Pharmacological Regimen with Lithium, Sertraline, and Bupropion Hydrochloride in Bipolar Depression Post First-Line Treatment Failure
Data & Insights
Has run more than one trial at 17 of 92 partner sites.
Specializations
Depression Research
This investigator specializes in studying various forms of depression, with particular emphasis on treatment-resistant depression (TRD) and major depressive disorder (MDD). Their research extends to anhedonia in the context of depression and innovative treatment approaches for patients who have experienced first-line treatment failures.
- Treatment-resistant depression interventions
- Major depressive disorder management
- Anhedonia-focused therapies
The investigator evaluates treatment responses using standardized assessment tools such as the Montgomery Åsberg Depression Rating Scale (MADRS).
Schizophrenia Spectrum Disorders
The investigator conducts research in the field of schizophrenia spectrum disorders, including schizoaffective disorder and schizophreniform disorder. Their work focuses on early intervention strategies and treatment optimization for patients experiencing first-line treatment failures.
- Schizophrenia treatment optimization
- Schizoaffective disorder management
- Early intervention protocols
Treatment efficacy is evaluated using the Positive And Negative Syndrome Scale (PANSS).
Bipolar Disorder Studies
Research interests include the treatment of bipolar depression, with specific focus on bipolar disorder type I and II. The investigator studies intensified pharmacological interventions for patients who have not responded adequately to initial treatments.
- Bipolar depression management
- Treatment resistance strategies
- Early intervention approaches
The research encompasses both acute treatment responses and long-term management strategies.
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