Bernadette R.
- Country
- Hungary
- Department
- N/A
Research Overview
Data & Insights
Has run more than one trial at 0 of 34 partner sites.
Specializations
Rheumatoid Arthritis Therapeutics
Investigation of biologic and targeted synthetic disease‑modifying agents for moderate to severe Rheumatoid Arthritis, especially after inadequate response to prior therapy.
- Upadacitinib
- Adalimumab
- Nipocalimab
- Burfiralimab
- IMVT‑1402
Emphasis on combination strategies and novel mechanisms of action.
Axial Spondyloarthritis Management
Evaluation of Janus kinase inhibition and comparative efficacy with placebo in active Axial Spondyloarthritis, covering both radiographic and non‑radiographic disease.
- Upadacitinib
- bDMARD‑IR Ankylosing Spondylitis
- nr‑axSpA
Includes safety assessment in patients refractory to conventional biologics.
Systemic Lupus Erythematosus Immunomodulation
Assessment of type‑I interferon blockade to reduce overall disease activity in adult Systemic Lupus Erythematosus patients.
- Anifrolumab
- Placebo‑controlled design
- Disease activity measures
Targets innate immune pathways implicated in lupus pathogenesis.
Systemic Sclerosis‑Associated Interstitial Lung Disease
Study of an antifibrotic agent’s impact on forced vital capacity decline in patients with Systemic Sclerosis‑Associated Interstitial Lung Disease, a form of connective‑tissue‑related lung involvement.
- MK‑7240/PRA023
- FVC change
- Placebo comparison
Safety and tolerability monitored over a 50‑week period.
Venous Thromboembolism Prevention in Orthopedic Surgery
Evaluation of monoclonal antibody prophylaxis to reduce postoperative clot formation, specifically Venous Thromboembolism, after knee arthroplasty.
- REGN9933
- REGN7508
- Enoxaparin comparator
- Unilateral total knee arthroplasty
Focus on efficacy and safety within a surgical patient population.
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