Benjamin L.
- Country
- France
- Department
- Medical oncology
Research Overview
- PRODIGE 81-FFCD 2101-TRIPLET: Randomized, open-label, phase II-III study evaluating the benefit of adding Ipilimumab to the combination of Atezolizumab and Bevacizumab in patients with hepatocellular carcinoma receiving first-line systemic therapy
- Phase III Randomized Study of Induction Chemotherapy with Modified DCF Regimen Followed by Chemoradiotherapy vs. Standard Chemoradiotherapy in Locally Advanced Anal Squamous Cell Carcinoma
- Phase II Randomized Trial of FOLFIRINOX Plus Panitumumab Versus mFOLFOX6 Plus Panitumumab in RAS/B-RAF Wild-Type Metastatic Colorectal Cancer
Data & Insights
Has run more than one trial at 126 of 253 partner sites.
Specializations
Breast cancer and gynaecological oncology
Benjamin LINOT is involved in clinical research on breast cancer, including triple-negative breast cancer, hormone receptor-positive and HER2-negative disease, as well as HER2-positive metastatic breast cancer. His activity also extends to ovarian cancer, endometrial cancer, cervical cancer, and biliary tract cancer, with interest in advanced and recurrent settings.
- Triple-negative breast cancer
- ER-positive / HER2-negative breast cancer
- Ovarian and fallopian tube cancer
- Endometrial and cervical cancer
- Biliary tract cancer
His research landscape includes targeted therapy, immunotherapy, PARP inhibition, and treatment strategies aimed at recurrence control in advanced gynaecological malignancies.
Thoracic oncology and lung cancer
His clinical trial involvement covers non-small cell lung cancer, including early-stage, locally advanced, and metastatic disease, as well as small cell lung cancer. The research portfolio also includes molecularly selected populations such as EGFR-mutated, KRAS G12C-positive, and PD-L1-defined lung cancer.
- Non-small cell lung cancer
- Small cell lung cancer
- EGFR-mutated disease
- PD-L1-selected tumours
- Radiation-based lung cancer management
He is active in studies involving checkpoint inhibitors, antibody-drug conjugates, and combined radiotherapy approaches for thoracic malignancies.
Haematology and lymphoid malignancies
Benjamin LINOT participates in trials focused on chronic lymphocytic leukemia, follicular lymphoma, diffuse large B-cell lymphoma, peripheral T-cell lymphoma, multiple myeloma, and myelodysplastic syndromes. His activity also includes Waldenström macroglobulinemia and other myeloid neoplasms.
- Chronic lymphocytic leukemia
- Follicular and diffuse large B-cell lymphoma
- Peripheral T-cell lymphoma
- Multiple myeloma
- Myelodysplastic and myeloproliferative disorders
His therapeutic interests include B-cell–directed therapies, bispecific antibodies, cellular immunotherapy, and novel combinations for relapsed or treatment-naïve haematologic cancers.
Digestive oncology and genitourinary cancers
His research activity includes colorectal cancer, rectal cancer, colon cancer, esophagogastric cancer, stomach cancer, and hepatocellular carcinoma. In genitourinary oncology, he is involved in studies of prostate cancer, renal cell carcinoma, and urothelial carcinoma.
- Colorectal and rectal cancer
- Gastric and gastro-oesophageal cancer
- Hepatocellular carcinoma
- Prostate cancer
- Renal cell and urothelial carcinoma
His work reflects interest in biomarker-guided treatment, anti-angiogenic therapy, and immune-based strategies across advanced solid tumours.
Head and neck cancer, bone disease, and cardiovascular prevention
Benjamin LINOT is also involved in trials in head and neck squamous cell carcinoma, anal cancer, and selected bone metastases requiring local treatment approaches. His portfolio further includes atrial fibrillation and coronary artery disease, showing interest in antithrombotic and cardiovascular prevention research.
- Head and neck squamous cell carcinoma
- Anal squamous cell carcinoma
- Vertebral metastases
- Atrial fibrillation
- Coronary artery disease
His therapeutic scope includes radiation-based oncology and antithrombotic strategies, linking cancer care with supportive and preventive medical innovation.
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