Bénédicte O.
- Country
- France
- Department
- Dermatology
Research Overview
- Efficacy and Safety Evaluation of Tulisokibart in Moderate to Severe Hidradenitis Suppurativa: A Phase 2b Randomized, Double-Blind, Placebo-Controlled Trial
- A Seamless Phase 2a/2b, Randomized, Double-Blind, Placebo- and Active-Controlled, Multiple-Arm, Multiple-Stage, Adaptive Study Evaluating the Efficacy and Safety of LAD191 in Adults With Moderate-to-Severe Hidradenitis Suppurativa
Data & Insights
Has run more than one trial at 3 of 42 partner sites.
Specializations
Dermatology and inflammatory skin disease
Clinical research activity in dermatology includes work on chronic inflammatory and immune-mediated skin disorders, with attention to conditions that require targeted control of cutaneous inflammation and symptom burden.
- Atopic dermatitis
- Psoriasis
- Hidradenitis suppurativa
- Vitiligo
- Cutaneous lupus erythematosus
This area also encompasses severe or refractory autoimmune skin disease and other dermatologic conditions linked to systemic immune dysfunction.
Autoimmune and systemic inflammatory disorders
The investigator is involved in clinical research on autoimmune disease and multisystem inflammatory conditions, including disorders affecting the joints, connective tissue, and vasculature.
- Systemic lupus erythematosus
- Lupus nephritis
- Sjögren’s syndrome
- Rheumatoid arthritis
- Systemic sclerosis
Additional interests extend to vasculitis, myositis, and other immune-mediated rheumatic diseases with significant organ involvement.
Oncology and solid tumor therapeutics
Research activity also covers oncology, with focus on advanced solid tumors and malignancies where new systemic strategies are being explored across skin, lung, gastrointestinal, and genitourinary cancers.
- Non-small cell lung cancer
- Colorectal cancer
- Hepatocellular carcinoma
- Breast cancer
- Melanoma
This domain includes interest in precision oncology and treatment approaches for advanced or unresectable disease.
Gastroenterology and immune-mediated bowel disease
The investigator is engaged in studies of inflammatory bowel disease and related gastrointestinal inflammation, with emphasis on chronic relapsing disorders requiring long-term disease control.
- Crohn’s disease
- Ulcerative colitis
- Primary sclerosing cholangitis
- Gastrointestinal inflammation
- Digestive autoimmune disease
Therapeutic interests also include associated hepatobiliary and systemic complications linked to chronic intestinal inflammation.
Rare disease and immune-mediated organ involvement
Clinical trial involvement extends to rare diseases and complex immune-mediated disorders affecting the kidney, lung, and nervous system, reflecting a broad therapeutic scope beyond dermatology.
- IgA nephropathy
- Interstitial lung disease
- Myasthenia gravis
- Systemic mastocytosis
- Amyloidosis
These interests include orphan inflammatory disorders and conditions where immune modulation is central to therapeutic development.
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