B.R. K.
- Country
- The Netherlands
- Department
- Department of Surgery
Research Overview
Data & Insights
Has run more than one trial at 0 of 16 partner sites.
Specializations
Oncology – Solid Tumors
The investigator concentrates on advanced solid malignancies, addressing therapeutic sequencing for cancers of the lung, kidney, prostate, colon, pancreas, and urinary tract.
- non-small cell lung cancer
- renal cell carcinoma
- prostate cancer
- colorectal cancer
- pancreatic ductal adenocarcinoma
- urothelial carcinoma
Research emphasizes neoadjuvant and adjuvant strategies to improve surgical outcomes and long‑term survival.
Cardiovascular & Metabolic Disease
Clinical work targets major arterial disease, acute coronary events, cardiac rhythm disorders, and lipid abnormalities.
- atherosclerotic cardiovascular disease
- acute coronary syndrome
- atrial fibrillation
- hypertriglyceridemia
- lipoprotein(a) elevation
Efforts focus on preventing major adverse cardiovascular events through innovative pharmacologic interventions.
Renal & Glomerular Disorders
Investigations address immune‑mediated kidney diseases, aiming to preserve renal function and reduce protein loss.
- IgA nephropathy
- C3 glomerulopathy
- lupus nephritis
- proteinuria
- renal function preservation
Therapeutic goals include stabilizing glomerular injury and limiting progression to chronic kidney disease.
Autoimmune & Inflammatory Diseases
The investigator engages in studies of systemic autoimmunity and gastrointestinal inflammation, seeking disease‑modifying outcomes.
- systemic lupus erythematosus
- Crohn's disease
- ulcerative colitis
- systemic sclerosis
- Behçet's disease
Key endpoints include remission of disease activity and improvement in patient‑reported quality of life.
Rare Genetic & Neurological Disorders
Research extends to hereditary muscular dystrophies, neurodegenerative movement disorders, and retinal degenerations.
- Duchenne muscular dystrophy
- Parkinson's disease
- retinitis pigmentosa
- facioscapulohumeral muscular dystrophy
- geographic atrophy
Therapeutic initiatives aim to alter disease progression and preserve functional capacity.
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