Ava D.
- Country
- France
- Department
- Maladies Infectieuses et Tropicales
Research Overview
- Non‑inferiority of oral fosfomycin versus fluoroquinolone or TMP‑SMX combination therapy as step‑down treatment for febrile urinary tract infection in men caused by Escherichia coli
- Efficacy of Prednisone Adjunct to Antibiotic Therapy in Adults with Septic Arthritis: A Randomized Double-Blind Controlled Trial
Data & Insights
Has run more than one trial at 5 of 27 partner sites.
Specializations
Nontuberculous Mycobacterial Infections
Focused on pulmonary disease caused by Mycobacterium avium complex in newly diagnosed adult patients.
- Diagnosis and management of NTM lung disease
- Antimicrobial regimens for MAC infections
- Outcomes of treatment in immunocompetent versus immunocompromised hosts
Research conducted at major Parisian hospitals supports therapeutic optimization for this emerging infection.
Viral Hepatitis and HIV
Investigates chronic infections with Hepatitis B virus, Hepatitis C virus and Human Immunodeficiency Virus in diverse patient populations.
- Long‑term antiviral efficacy and safety
- Co‑infection management strategies
- Impact of viral suppression on liver disease progression
Studies leverage the expertise of Assistance Publique – Hôpitaux de Paris for multicenter enrollment.
Sepsis and Critical Care Infectious Diseases
Addresses severe bacterial infections and septic shock in adult intensive‑care units.
- Pathogen‑directed antibiotic therapy in ICU patients
- Biomarker‑guided treatment algorithms
- Outcomes of invasive mechanical ventilation related infections
Collaboration with Hopital Beaujon provides access to a high‑volume critical‑care cohort.
Autoimmune and Inflammatory Disorders
Specializes in systemic autoimmune diseases such as primary Sjögren's syndrome and ANCA‑associated vasculitis.
- Immunomodulatory treatment efficacy
- Clinical phenotyping of organ‑specific involvement
- Longitudinal monitoring of disease activity
Research integrates rheumatology and infectious disease expertise to optimize patient care.
Amyloidosis and Neuropathy
Explores hereditary transthyretin amyloidosis with polyneuropathy and related cardiomyopathy.
- Genotype‑phenotype correlation in ATTR
- Therapeutic impact of TTR stabilizers
- Neurological and cardiac outcome measures
Studies aim to define disease‑modifying strategies for this rare systemic disorder.
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