Audrey R.
- Country
- France
- Department
- #2109: Neurology
Research Overview
Data & Insights
Has run more than one trial at 0 of 57 partner sites.
Specializations
Neurovascular Disorders
Focused on the pathophysiology and therapeutic strategies for acute ischemic stroke and related cerebrovascular events, including high‑risk transient ischemic attacks.
- Thrombolytic and neuroprotective interventions
- Secondary prevention in stroke survivors
- Imaging biomarkers for early reperfusion
Research aims to reduce disability and improve functional recovery through targeted vascular and neuronal protection.
Neurodegenerative Disorders
Investigates disease‑modifying approaches for Alzheimer’s disease, Parkinson’s disease and Amyotrophic Lateral Sclerosis, emphasizing early diagnosis and biomarker‑guided therapy.
- Protein aggregation inhibition
- Neuroinflammation modulation
- Neuroprotective small molecules
The goal is to slow progression and preserve cognitive and motor function.
Neuroimmunology and Autoimmune Neurology
Examines autoimmune mechanisms underlying multiple sclerosis, neuromyelitis optica spectrum disorder and myasthenia gravis, with a therapeutic focus on monoclonal antibodies and immunomodulators.
- Targeted B‑cell depletion
- Complement inhibition strategies
- Novel antigen‑specific tolerance induction
Efforts aim to achieve durable remission and reduce relapse rates.
Central Nervous System Tumors
Specializes in adult and pediatric glioblastoma, medulloblastoma and ependymoma management, integrating surgical, radiotherapeutic and molecularly targeted approaches.
- Precision oncology based on tumor genetics
- Combination of immunotherapy with standard care
- Neuro‑oncologic quality‑of‑life outcomes
The objective is to extend survival while preserving neurological function.
Rare Genetic Neurological Disorders
Addresses inherited conditions such as Huntington’s disease, spinocerebellar ataxia and familial Mediterranean fever, focusing on genotype‑phenotype correlation and precision‑medicine interventions.
- Gene‑silencing and editing techniques
- Biomarker development for disease monitoring
- Therapeutic repurposing for neuro‑inflammatory pathways
Research seeks to translate molecular insights into targeted clinical therapies.
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