Attilio G.
- Country
- Italy
- Department
- Ematologia
Research Overview
- Phase 3 Randomized Study of Epcoritamab Plus R-CHOP Versus R-CHOP in Newly Diagnosed Diffuse Large B-Cell Lymphoma Patients
- Phase 3 Open-Label Evaluation of Epcoritamab with Rituximab and Lenalidomide in Relapsed/Refractory Follicular Lymphoma
- Efficacy and Safety Comparison of Venetoclax and Obinutuzumab Versus FCR/BR in Fit Patients with Untreated Chronic Lymphocytic Leukemia Without DEL(17P) or TP53 Mutation
Data & Insights
Has run more than one trial at 96 of 267 partner sites.
Specializations
Thoracic Oncology
Clinical research activity is strongly centered on non-small cell lung cancer, with interest in resectable, locally advanced, and metastatic disease, as well as biomarker-defined subgroups such as EGFR, ALK, ROS1, RET, and KRAS G12C alterations.
- Small cell lung cancer
- Pleural mesothelioma
- Head and neck squamous cell carcinoma
- Lung cancer adjuvant and perioperative treatment
The portfolio also includes immunotherapy, targeted therapy, and combined modality approaches in thoracic malignancies.
Melanoma and Other Skin Cancers
Another major area of interest is melanoma, including advanced cutaneous melanoma, mucosal melanoma, uveal melanoma, and resected high-risk melanoma, alongside other skin cancers such as cutaneous squamous cell carcinoma and Merkel cell carcinoma.
- Advanced unresectable melanoma
- Adjuvant melanoma therapy
- Cutaneous squamous cell carcinoma
- Merkel cell carcinoma
Research activity in this field reflects a focus on checkpoint-based immunotherapy and post-surgical recurrence prevention in high-risk disease.
Hematologic Malignancies
The hematology portfolio includes acute myeloid leukemia with molecularly defined subtypes, chronic lymphocytic leukemia, small lymphocytic lymphoma, and multiple non-Hodgkin lymphomas such as diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, and marginal zone lymphoma.
- Myelofibrosis
- Myelodysplastic syndromes
- Hodgkin lymphoma
- Primary central nervous system lymphoma
Therapeutic interest extends to BTK inhibition, anti-CD20-based regimens, and novel lymphoma-directed treatments.
Genitourinary and Gynecologic Cancers
Clinical trial involvement also spans bladder cancer, urothelial carcinoma, endometrial cancer, ovarian cancer, fallopian tube cancer, and peritoneal cancer, with attention to both advanced and recurrent settings.
- Muscle-invasive bladder cancer
- Non-muscle invasive bladder cancer
- HER2-expressing endometrial cancer
- Advanced epithelial ovarian cancer
These studies include perioperative treatment, maintenance strategies, and biomarker-selected therapy in solid tumors of the urinary and female reproductive tracts.
Precision Oncology and Rare Solid Tumors
Additional research interests cover colorectal cancer, gastric and gastroesophageal cancer, breast cancer, pancreatic ductal adenocarcinoma, rectal cancer, and small bowel adenocarcinoma, with frequent emphasis on molecularly selected populations.
- HER2-low and HER2-positive breast cancer
- Metastatic colorectal cancer
- Rare sarcoma and solid tumor indications
- Venous thromboembolism in cancer
The therapeutic landscape includes antibody-drug conjugates, targeted agents, and tumor biomarker-driven treatment selection.
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