Atanas B.
- Country
- Bulgaria
- Department
- Third Department of Clinical Hematology at Clinical Hematology Clinic
Research Overview
- Pharmacokinetic Evaluation of Efanesoctocog Alfa Versus Other Extended Half-Life Recombinant Factor VIII Products in Severe Haemophilia A Patients
- Continuation Study on Efanesoctocog Alfa for Safety and Efficacy in Severe Haemophilia A Patients Post-Previous Trial Completion
- Evaluation of Treatment Strategies in Haemophilia A Patients with FVIII Inhibitors Using Simoctocog Alfa, Emicizumab, and Drug Combination
Data & Insights
Has run more than one trial at 16 of 70 partner sites.
Specializations
Pediatric Hematology and Benign Blood Disorders
Clinical research activity is centered on pediatric hematology in children and adolescents with benign hematological diseases, with a strong focus on bleeding disorders, thrombocytopenia, and inherited coagulation conditions.
- Haemophilia A and Haemophilia B
- Immune Thrombocytopenia
- Moderate thrombocytopenia
- Hemophilia with or without inhibitors
The investigator is linked to specialized hematology sites in Sofia, supporting access to studies in coagulation disorders and other non-malignant blood diseases in the pediatric setting.
Myeloid and Lymphoid Malignancies
Research involvement extends to hematologic malignancies, especially diseases affecting the myeloid and lymphoid lineages, including relapsed, newly diagnosed, and higher-risk subgroups.
- Acute myeloid leukemia
- Myelodysplastic syndrome
- Chronic myeloid leukemia
- Chronic lymphocytic leukemia and small lymphocytic lymphoma
Additional interest includes myelofibrosis, follicular lymphoma, diffuse large B-cell lymphoma, and related marrow failure or overlap disorders.
Gastroenterology and Inflammatory Bowel Disease
The clinical portfolio includes substantial activity in immune-mediated gastrointestinal disease, particularly chronic inflammatory conditions requiring long-term therapeutic management.
- Crohn's Disease
- Ulcerative Colitis
- Moderately to severely active Crohn's disease
- Moderately to severely active ulcerative colitis
Related interests also cover erosive esophagitis and broader gastrointestinal inflammation, reflecting engagement with therapies for chronic digestive tract disease.
Cardiovascular and Metabolic Disease
Another major area of involvement is cardiovascular medicine, including prevention and treatment strategies for patients with elevated thrombotic, lipid, and blood pressure-related risk.
- Atrial Fibrillation
- Heart Failure
- Atherosclerotic Cardiovascular Disease
- Hypertriglyceridemia
Clinical interest also includes resistant hypertension, uncontrolled hypertension, obesity, and cardiometabolic risk reduction.
Oncology, Autoimmune Disease, and Other Therapeutic Areas
The trial landscape further includes selected work in solid tumors, breast cancer, lung cancer, urothelial cancer, and head and neck squamous cell carcinoma, alongside immune and inflammatory conditions.
- Advanced Breast Cancer
- Non-Small Cell Lung Cancer
- Advanced prostate cancer
- Hidradenitis Suppurativa
Additional therapeutic interests include multiple sclerosis, chronic spontaneous urticaria, myasthenia gravis, and contrast-enhanced magnetic resonance imaging in children.
Related Investigators
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