Astrid T.
- Country
- France
- Department
- Radiotherapy
Research Overview
- Phase I/II Study of Stereotactic Ablative Reirradiation with Metformin for Relapse in Previously Irradiated Prostate Bed (REPAIR GETUG P16)
- Phase 3 Randomized, Double-blind, Placebo-controlled Study of Apalutamide and GnRH Agonist in High-risk Localized or Locally Advanced Prostate Cancer with Primary Radiation Therapy
- Evaluation of Darolutamide and Stereotactic Dose-Escalated Radiotherapy in High-Risk Localized Prostate Cancer: A Phase III Randomized Trial
Data & Insights
Has run more than one trial at 15 of 119 partner sites.
Specializations
Radiation Oncology and Head and Neck Cancer
Astrid THOMIN’s clinical research activity is centered on radiation oncology, with a strong focus on malignancies of the head and neck, including sinonasal tumors, salivary gland carcinomas, and locally advanced or recurrent disease requiring combined local treatment strategies.
- Head and neck squamous cell carcinoma
- Sinonasal and salivary gland malignancies
- Locally advanced unresectable disease
- Adjuvant and definitive radiotherapy
Her work also includes therapeutic interest in treatment optimization for patients with residual, recurrent, or inoperable tumors in the cervicofacial region.
Thoracic Malignancies
She is actively involved in clinical research on lung cancer, with emphasis on non-small cell lung cancer and small cell lung cancer, including advanced, metastatic, and unresectable presentations where multimodal oncologic care is relevant.
- Non-small cell lung cancer
- Small cell lung cancer
- Locally advanced thoracic tumors
- Metastatic pulmonary disease
Her therapeutic landscape also extends to post-treatment settings in which disease control and consolidation approaches are important.
Breast and Gynecologic Oncology
Another major area of interest is breast cancer, particularly HER2-positive, hormone receptor-positive, and triple-negative breast cancer, alongside ovarian cancer, endometrial cancer, and cervical cancer.
- HER2-positive breast cancer
- Triple-negative breast cancer
- Ovarian and endometrial cancer
- Cervical cancer
Her involvement reflects a therapeutic interest in both early-stage and advanced solid tumors where systemic treatment and local control intersect.
Hematologic Malignancies
Her clinical research portfolio includes a broad range of hematologic cancers, especially acute leukemia, chronic lymphocytic leukemia, lymphoma, multiple myeloma, and myelodysplastic syndromes.
- Acute lymphoblastic leukemia
- Acute myeloid leukemia
- B-cell lymphoma
- Multiple myeloma
She is also engaged in research on high-risk and relapsed or refractory blood cancers, including entities requiring specialized oncologic management.
Supportive and Cross-Disciplinary Oncology Care
Her trial involvement also touches on supportive cancer care and treatment-related complications, including infectious complications, cardiovascular risk, kidney disease, and immune-mediated disorders encountered in oncologic practice.
- Infection-related complications
- Cardio-oncology
- Renal impairment in cancer care
- Immune and inflammatory toxicities
These areas align with clinical innovation in improving treatment tolerance and maintaining disease control across complex oncology populations.
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