Arsène M.
- Country
- France
- Department
- internal medicine
Research Overview
- Phase II Study Evaluating the Efficacy and Safety of Secukinumab versus Combination Therapy in Patients with Active Severe Takayasu Arteritis
- Efficacy of Tocilizumab with Steroids in Giant Cell Arteritis with Cerebrovascular Involvement: A Randomized, Placebo-Controlled Phase III Trial
- Efficacy and Safety of Prednisone Plus Rivaroxaban Versus Prednisone Alone in Deep Venous Thrombosis of Behçet’s Syndrome: A Randomized Controlled Trial
Data & Insights
Has run more than one trial at 42 of 88 partner sites.
Specializations
Internal Medicine and Autoimmune Disease
Clinical research activity includes systemic lupus erythematosus, lupus nephritis, primary Sjögren’s syndrome, systemic sclerosis, and vasculitis, with additional involvement in idiopathic inflammatory myopathies and rheumatologic inflammation.
- Systemic lupus erythematosus
- Lupus nephritis
- Primary Sjögren’s syndrome
- ANCA-associated vasculitis
- Systemic sclerosis
Therapeutic interests extend to immune-mediated organ involvement, connective tissue diseases, and inflammatory kidney disease.
Hematology and Blood Cancers
Research involvement spans acute myeloid leukemia, acute lymphoblastic leukemia, myelodysplastic syndromes, chronic lymphocytic leukemia, and multiple myeloma, with additional work in lymphomas and other hematologic malignancies.
- Acute myeloid leukemia
- Acute lymphoblastic leukemia
- Multiple myeloma
- Diffuse large B-cell lymphoma
- Myelodysplastic syndromes
The therapeutic profile also includes relapsed and refractory disease, transplant-related care, and B-cell malignancies.
Gastroenterology, Hepatology, and Inflammatory Bowel Disease
Clinical trial activity covers Crohn’s disease, ulcerative colitis, primary sclerosing cholangitis, primary biliary cholangitis, and hepatocellular carcinoma, alongside broader work in biliary tract cancer and gastrointestinal malignancies.
- Crohn’s disease
- Ulcerative colitis
- Primary sclerosing cholangitis
- Primary biliary cholangitis
- Hepatocellular carcinoma
Therapeutic focus includes immune-driven digestive disease, cholestatic liver disease, and advanced gastrointestinal cancer.
Oncology and Solid Tumor Therapy
Research interests include non-small cell lung cancer, colorectal cancer, gastric and gastroesophageal junction cancer, breast cancer, melanoma, and urothelial carcinoma, with activity across multiple advanced solid tumors.
- Non-small cell lung cancer
- Colorectal cancer
- Gastric cancer
- Breast cancer
- Urothelial carcinoma
The therapeutic landscape also reflects interest in targeted oncology, immuno-oncology, and advanced metastatic disease.
Cardiometabolic, Renal, and Rare Disease Research
Additional clinical activity involves atherosclerotic cardiovascular disease, heart failure, acute coronary syndromes, chronic kidney disease, IgA nephropathy, and amyloidosis, as well as selected rare genetic disorders and immunologic syndromes.
- Atherosclerotic cardiovascular disease
- Heart failure
- Chronic kidney disease
- IgA nephropathy
- Transthyretin amyloidosis
Therapeutic domains include cardiovascular risk reduction, renal protection, and rare systemic disease management.
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