Clinical Research
person

Apostolos K.

Country
Greece
Department
Cardiology Clinic

Research Overview

assignment
10
Clinical Trials ·
location_city
1
Research Sites

Data & Insights

medical_services
Primary Speciality
Main therapeutic area

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Return Partnerships
Recurring site collaborations
496
Sites with multiple studies

Has run more than one trial at 496 of 1193 partner sites.

Specializations

Cardiovascular disease and cardiometabolic risk

Clinical research activity is centered on atherosclerotic cardiovascular disease, heart failure, atrial fibrillation, myocardial infarction, stroke prevention, and hypertension, with additional interest in risk reduction for patients with obesity, type 2 diabetes, and elevated lipoprotein(a).

  • Heart failure and heart failure with preserved ejection fraction
  • Atrial fibrillation and cardioembolic event prevention
  • Acute myocardial infarction and ischemic stroke
  • Atherosclerotic cardiovascular disease and resistant hypertension

Work in this area also extends to cardiovascular inflammation, prevention of recurrent events, and treatment strategies for patients with overlapping metabolic and renal risk.

Respiratory medicine and thoracic oncology

The investigator is actively involved in studies spanning non-small cell lung cancer, small cell lung cancer, melanoma, and other solid tumors, alongside chronic respiratory disorders such as chronic obstructive pulmonary disease, asthma, and idiopathic pulmonary fibrosis.

  • Non-small cell lung cancer with molecularly defined subtypes
  • Small cell lung cancer and extensive-stage disease
  • Melanoma and metastatic solid tumors
  • COPD, asthma, and idiopathic pulmonary fibrosis

This portfolio reflects interest in advanced thoracic malignancies, immune-based cancer treatment, and chronic pulmonary disease management.

Autoimmune and inflammatory diseases

Research involvement includes systemic lupus erythematosus, rheumatoid arthritis, Sjögren’s syndrome, systemic sclerosis, and antineutrophil cytoplasmic antibody-associated vasculitis, as well as inflammatory bowel conditions such as Crohn’s disease and ulcerative colitis.

  • Systemic lupus erythematosus and cutaneous lupus erythematosus
  • Rheumatoid arthritis and axial spondyloarthritis
  • Sjögren’s syndrome and systemic sclerosis
  • Crohn’s disease and ulcerative colitis

Additional interest is seen in immune-mediated organ involvement, including vasculitis, thyroid eye disease, and other chronic inflammatory disorders.

Hematology and hematologic malignancies

The clinical trial profile includes diffuse large B-cell lymphoma, follicular lymphoma, chronic lymphocytic leukemia, myelodysplastic syndrome, myelofibrosis, and acute myeloid leukemia, together with inherited and acquired blood disorders.

  • Diffuse large B-cell lymphoma and follicular lymphoma
  • Chronic lymphocytic leukemia and mantle cell lymphoma
  • Myelodysplastic syndrome and myelofibrosis
  • Hemophilia and thalassemia

There is also involvement in plasma cell disorders, paroxysmal nocturnal hemoglobinuria, and other complex blood and lymphatic diseases.

Renal, infectious, and gastrointestinal disease

Additional research areas include chronic kidney disease, IgA nephropathy, complement-mediated renal disease, hepatitis B, hepatitis C, COVID-19, sepsis, and serious bacterial or fungal infections, alongside selected gastrointestinal and liver disorders.

  • Chronic kidney disease and IgA nephropathy
  • Hepatitis B, hepatitis C, and alcohol-related liver disease
  • COVID-19, sepsis, and severe infections
  • Crohn’s disease, ulcerative colitis, and Clostridioides difficile infection

Work in this domain also covers pneumonia, candidiasis, and other difficult-to-treat infectious complications.

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