Antonio L. C.
- Country
- Spain
- Department
- Servicio de Medicina Interna
Research Overview
- Evaluation of Safety and Efficacy of Elacestrant in Combination Therapies for Patients with Metastatic Breast Cancer: A Phase 1b/2 Open-Label Umbrella Study
- Efficacy and Safety of Giredestrant vs. Fulvestrant with CDK4/6 Inhibitor in ER+ HER2- Advanced Breast Cancer Resistant to Endocrine Therapy
- Phase III Randomized Trial of Trastuzumab, Alpelisib, and Fulvestrant Versus Trastuzumab and Chemotherapy in PIK3CA-Mutated HER2+ Advanced Breast Cancer
Data & Insights
Has run more than one trial at 251 of 495 partner sites.
Specializations
Breast Cancer and HER2-Directed Therapy
Antonio Llombart is involved in clinical research across early breast cancer, advanced breast cancer, and metastatic breast cancer, with a strong focus on HER2-positive, HER2-low, and hormone receptor-positive disease. His work also includes triple-negative breast cancer and treatment strategies linked to recurrence prevention and residual disease.
- HER2-targeted therapy
- Endocrine therapy in breast cancer
- Antibody-drug conjugates
- Triple-negative breast cancer
- Early-stage breast cancer
His research landscape also extends to biomarker-informed approaches in PIK3CA-mutated and ESR1-mutated breast cancer, as well as studies addressing brain metastases and leptomeningeal disease.
Thoracic Oncology and Lung Cancer
His clinical trial activity includes multiple settings of non-small cell lung cancer, small-cell lung cancer, and broader solid tumors, with interest in both locally advanced and metastatic disease. This area reflects involvement in immunotherapy-based and targeted treatment strategies for thoracic malignancies.
- Non-small cell lung cancer
- Extensive-stage small-cell lung cancer
- Metastatic solid tumors
- Brain metastases from lung cancer
His portfolio also covers patients with advanced disease involving the central nervous system, including trials focused on intracranial response and treatment options for difficult-to-manage metastatic presentations.
Hematologic Malignancies
Antonio Llombart is active in studies of diffuse large B-cell lymphoma, follicular lymphoma, chronic lymphocytic leukemia, acute myeloid leukemia, and multiple myeloma. His research interests span both aggressive and indolent blood cancers, including treatment for relapsed, refractory, and previously untreated disease.
- Diffuse large B-cell lymphoma
- Chronic lymphocytic leukemia
- Follicular lymphoma
- Acute myeloid leukemia
- Multiple myeloma
His trial activity also includes B-cell lymphoma and other lymphoproliferative disorders, with attention to novel immunotherapy and targeted combinations in hematologic oncology.
Respiratory, Allergic, and Inflammatory Disease
His research includes severe asthma, chronic obstructive pulmonary disease, chronic spontaneous urticaria, chronic inducible urticaria, and atopic dermatitis. This area reflects interest in airway inflammation, allergic disease, and chronic immune-mediated skin conditions.
- Severe asthma
- Chronic obstructive pulmonary disease
- Chronic spontaneous urticaria
- Atopic dermatitis
- Allergic rhinoconjunctivitis
His clinical portfolio also covers eosinophilic airway disease and other inflammatory disorders, supporting research into symptom control and disease modification in chronic allergic conditions.
Cardiometabolic, Hepatic, and Other Specialty Conditions
Antonio Llombart is also involved in studies of atherosclerotic cardiovascular disease, hypertension, elevated lipoprotein(a), NASH/MASH, and fibrotic liver disease. Additional research activity includes bladder cancer, neovascular age-related macular degeneration, and HIV-1 infection.
- Cardiovascular disease
- Metabolic dysfunction-associated steatohepatitis
- Bladder cancer
- Neovascular age-related macular degeneration
- HIV-1 infection
His trial portfolio further includes anticoagulation reversal, insomnia disorder, and mechanical ventilation weaning, showing engagement with diverse therapeutic areas beyond oncology.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.