Antonio J. R.
- Country
- Spain
- Department
- Onco hematologia pediatrica
Research Overview
- ONC201 for the Treatment of Newly Diagnosed H3 K27M-mutant Diffuse Glioma Following Completion of Radiotherapy: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study (The ACTION Study)
- Phase 1b/2 Study of Ifinatamab Deruxtecan in Pediatric Patients with Relapsed or Refractory Solid Tumors (Neuroblastoma, Rhabdomyosarcoma, Wilms Tumor, Osteosarcoma)
- Randomized Phase II/III Study of Cabozantinib Maintenance Versus Best Supportive Care in Osteosarcoma Patients After First‑Line Chemotherapy (FOSTER‑CabOS)
Data & Insights
Has run more than one trial at 128 of 251 partner sites.
Specializations
Paediatric haematology and leukaemia
Antonio Juan Ribelles is involved in clinical research across acute lymphoblastic leukaemia, acute myeloid leukaemia, myelodysplastic syndromes, and related myeloid malignancies, with activity that also extends to relapsed and refractory blood cancers in children and young adults.
- Acute lymphoblastic leukaemia
- Acute myeloid leukaemia
- Myelodysplastic syndromes
- Relapsed and refractory haematological malignancies
His work also includes haematopoietic stem cell transplantation-related care and malignancies with high unmet therapeutic need in the paediatric setting.
Paediatric oncology and solid tumours
His clinical trial portfolio includes a broad range of paediatric cancers and solid tumours, with particular attention to neuroblastoma, glioma, sarcoma, and advanced or recurrent malignancies requiring innovative treatment options.
- Neuroblastoma
- Glioma
- Sarcoma
- Advanced solid tumours
He is also involved in research on head and neck cancer, breast cancer, ovarian cancer, and renal cell carcinoma across paediatric and adolescent oncology contexts.
Immune-mediated inflammatory diseases
Antonio Juan Ribelles participates in studies of juvenile idiopathic arthritis, psoriatic arthritis, systemic lupus erythematosus, and other autoimmune diseases, reflecting a strong therapeutic interest in immune dysregulation and chronic inflammation.
- Juvenile idiopathic arthritis
- Psoriatic arthritis
- Systemic lupus erythematosus
- Crohn’s disease
His research also covers ulcerative colitis, Behçet’s disease, and systemic sclerosis, including conditions with paediatric onset or long-term inflammatory burden.
Neurology and neurodevelopmental disorders
His trial activity includes epilepsy, migraine, amyotrophic lateral sclerosis, and neurodegenerative diseases, alongside paediatric neurological disorders that require long-term disease control and symptom management.
- Epilepsy
- Migraine
- Amyotrophic lateral sclerosis
- Developmental and epileptic encephalopathies
He is also engaged in research on multiple sclerosis, Parkinson’s disease, and Alzheimer’s disease, covering both paediatric and adult neurological therapeutic areas.
Respiratory, transplant, and rare disease care
Antonio Juan Ribelles is active in trials addressing asthma, bronchiectasis, cystic fibrosis, and severe respiratory tract diseases, as well as post-transplant infectious prevention and immune complications.
- Asthma
- Cystic fibrosis
- Bronchiectasis
- Transplant-related infection prevention
His research interests further include rare genetic disorders, muscular dystrophies, and pulmonary hypertension, supporting care across complex chronic and orphan disease domains.
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