Antoine D.
- Country
- France
- Department
- Medical oncology
Research Overview
- Safety, Tolerability, and Anti-tumor Activity of HER3-DXd Monotherapy and Combinations in Advanced Breast Cancer Post-Trastuzumab Deruxtecan Progression
- Phase II PF-07248144 plus fulvestrant in advanced HR+/HER2- breast cancer after prior endocrine therapy and CDK4/6 inhibitor treatment
- Phase 3 Randomized Study of BGB‑43395 + Letrozole versus CDK4/6 Inhibitor Combination + Letrozole in Treatment‑Naïve Advanced HR+/HER2‑ Breast Cancer
Data & Insights
Has run more than one trial at 55 of 186 partner sites.
Specializations
Advanced Breast Cancer Research
The investigator specializes in treating hormone receptor-positive (HR+) and HER2-negative breast cancer, with particular emphasis on advanced and metastatic disease states. Their work encompasses evaluating novel therapeutic approaches for patients who have developed resistance to conventional treatments.
- ESR1 mutation detection and targeted therapies
- CDK4/6 inhibitor combination strategies
- Endocrine therapy resistance
Their expertise extends to investigating innovative treatment combinations for postmenopausal women with advanced breast cancer.
Early-Stage Breast Cancer
The investigator focuses on developing treatments for triple-negative breast cancer (TNBC) and exploring neoadjuvant therapeutic approaches. Their research includes evaluation of direct tumor intervention techniques and novel drug combinations.
- Intratumoral therapy development
- Neoadjuvant treatment strategies
- Biomarker assessment
Their work encompasses innovative approaches to early-stage breast cancer treatment, including targeted therapeutic interventions.
Precision Medicine Approaches
The investigator specializes in biomarker-driven treatment selection and personalized therapy approaches. Their research includes evaluation of circulating biomarkers and advanced imaging techniques for treatment optimization.
- PET/CT imaging assessment
- Circulating biomarker analysis
- Treatment response monitoring
Their expertise includes developing strategies for optimal treatment selection based on molecular and imaging markers.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.