Annie L.
- Country
- France
- Department
- Hépatologie
Research Overview
- Phase 3 Randomized Double‑Blind Placebo‑Controlled Study of Efimosfermin Alfa in Adults with Biopsy‑Confirmed F2–F3 Metabolic Dysfunction‑Associated Steatohepatitis
- Phase 3 Randomized Double‑Blind Placebo‑Controlled Study of Efimosfermin Alfa Safety and Tolerability in Adults with F2‑F3 Metabolic Dysfunction‑Associated Steatohepatitis
- Efficacy of Vedolizumab Versus Adalimumab Dose Intensification in Crohn's Disease Patients with Secondary Loss of Response to Adalimumab
Data & Insights
Has run more than one trial at 92 of 112 partner sites.
Specializations
Inflammatory Bowel Disease
Focus on therapeutic strategies for Crohn's disease using biologic agents and biomarker‑driven treatment adjustments.
- Biologic therapy optimization
- Biomarker monitoring
- Loss of response management
Emphasis on improving clinical remission and patient quality of life.
Colorectal Oncology and Surgical Outcomes
Investigates peri‑operative techniques to enhance safety in colorectal cancer resections.
- Anastomotic perfusion assessment
- Intraoperative imaging
- Leakage prevention
Integration of advanced visualization to support surgical decision‑making.
Musculoskeletal Pain Management
Explores regional anesthetic block interventions for acute lumbar pain associated with muscle contracture.
- Erector spinae muscle block
- Early pain control
- Functional recovery
Targets rapid alleviation of pain during the initial postoperative period.
Imaging and Fluorescence Guidance
Applies fluorescence angiography with indocyanine green to assess tissue perfusion in gastrointestinal surgery.
- Real‑time perfusion mapping
- Surgical margin assessment
- Complication reduction
Supports evidence‑based intraoperative decision processes.
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