Annette K.
- Country
- Norway
- Department
- Lungeavdelingen
Research Overview
- A Phase III, Multicentre, Randomized, Double-blind, Chronic-dosing, Parallel-group, Placebo-controlled Study to Evaluate the Efficacy and Safety of Two Dose Regimens of Tozorakimab in Participants with Symptomatic Chronic Obstructive Pulmonary Disease (COPD) with a History of COPD Exacerbations (Oberon)
- A Phase III, Multicentre, Randomised, Double-blind, Chronic-dosing, Parallel-group, Placebo-controlled Extension Study to Evaluate the Long-term Efficacy and Safety of Tozorakimab in Participants with Chronic Obstructive Pulmonary Disease (COPD) with a History of Exacerbations (PROSPERO)
Data & Insights
Has run more than one trial at 55 of 139 partner sites.
Specializations
Lung cancer and thoracic oncology
Clinical research in non-small cell lung cancer, small cell lung cancer, and other thoracic malignancies, with interest in immunotherapy, targeted treatment strategies, and disease control in advanced and recurrent settings.
- NSCLC
- SCLC
- EGFR-mutated disease
- PD-L1-directed therapy
Work also extends to treatment approaches for locally advanced disease and relapse prevention in lung cancer.
Hematologic malignancies and cellular therapy
Active involvement in studies of multiple myeloma, lymphoma, and acute lymphoblastic leukemia, including research on immune-based approaches, transplant-related care, and post-treatment disease monitoring.
- Relapsed/refractory multiple myeloma
- Acute lymphoblastic leukemia
- Lymphoma
- Gene-modified T-cell therapy
Therapeutic interests include hematologic cancer control, transplant support, and long-term follow-up after advanced immune therapies.
Autoimmune, inflammatory, and pulmonary disease
Research spans inflammatory bowel disease, primary sclerosing cholangitis, interstitial lung disease, and cystic fibrosis, reflecting a focus on chronic immune-mediated and respiratory disorders.
- Crohn’s disease
- Ulcerative colitis
- Primary sclerosing cholangitis
- Idiopathic pulmonary fibrosis
Additional interest is seen in systemic mastocytosis and other rare inflammatory conditions with unmet therapeutic need.
Cardiovascular and cerebrovascular medicine
Clinical trial activity includes atrial fibrillation, aortic stenosis, coronary artery disease, and stroke prevention, with emphasis on interventions that improve cardiovascular outcomes and rhythm control.
- Atrial fibrillation
- Aortic stenosis
- Coronary artery bypass grafting
- Ischemic stroke prevention
Interest also includes broader management of heart failure and thrombotic risk in high-risk cardiovascular disease.
Neurology, rare disease, and supportive care
Research involvement covers multiple sclerosis, migraine, dementia with Lewy bodies, and rare neurologic disorders, alongside supportive and symptom-focused therapeutic studies.
- Multiple sclerosis
- Migraine
- Dementia with Lewy bodies
- Rare neurologic disorders
Additional areas include myasthenia gravis, autism spectrum disorder, and treatment-related symptom management across complex chronic disease.
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