Anne-Sophie M.
- Country
- France
- Department
- Gastroenterology
Research Overview
- Phenotype-Guided Dose Adjustment of Fluoropyrimidine-Based Chemotherapy in Dihydropyrimidine Dehydrogenase Deficient Gastrointestinal Cancer Patients
- Phase III Randomized Trial of Adjuvant mFOLFIRINOX Versus Capecitabine or Gemcitabine in Resected Ampullary Adenocarcinoma Patients
- Neoadjuvant Encorafenib and Cetuximab in BRAF V600E-Mutated Localized Colon or Upper Rectum Cancer: A Multicenter Open-Label Pilot Study
Data & Insights
Has run more than one trial at 76 of 194 partner sites.
Specializations
Gastrointestinal Cancer Treatment
Specializes in personalized treatment approaches for patients with gastrointestinal cancers, particularly focusing on chemotherapy optimization for those with specific enzyme deficiencies.
- Fluoropyrimidine-based therapy management
- DPD deficiency assessment
- Chemotherapy dose individualization
Develops treatment guidelines for patients with enzyme-related therapeutic challenges.
Specialized Cancer Treatment
Focuses on advanced treatment protocols for ampullary adenocarcinoma and BRAF V600E-mutated colorectal cancers, implementing targeted therapeutic approaches.
- Modified FOLFIRINOX therapy
- Neoadjuvant treatment strategies
- Targeted molecular therapies
Investigates innovative combinations of targeted agents and established treatments.
Advanced Colorectal Cancer
Specializes in treating advanced colorectal adenocarcinoma with particular emphasis on KRAS G12C mutations and personalized treatment approaches.
- Targeted inhibitor therapies
- Combination treatment strategies
- Alternative treatment protocols
Develops treatment options for patients unsuitable for conventional chemotherapy regimens.
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