Anne-Cathrine B. Ø.
- Country
- Denmark
- Department
- Onkologisk Afdeling
Research Overview
- A translational RANDOMIZED phase III study exploring the effect of the addition of capecitabine to Carboplatinum based chemotherapy in early “triple negative” breast cancer
- Phase 3 Randomized Study of Datopotamab Deruxtecan ± Durvalumab vs. Investigator's Choice in Stage I-III Triple-negative Breast Cancer with Residual Disease
Data & Insights
Has run more than one trial at 12 of 93 partner sites.
Specializations
Oncologic Therapeutics – Breast Cancer
Focused investigation of Estrogen receptor‑positive HER2‑negative and triple‑negative breast cancer across early, locally advanced and metastatic settings, including post‑neoadjuvant residual disease.
- Estrogen receptor‑positive HER2‑negative breast cancer
- Triple‑negative breast cancer
- Neoadjuvant therapy residual disease
Research integrates targeted agents, antibody‑drug conjugates and novel combination regimens.
Prostate Cancer Therapeutics
Clinical activity centered on metastatic castration‑sensitive prostate cancer, HRR gene‑mutated prostate cancer and progression to metastatic castration‑resistant prostate cancer, exploring hormonal and DNA‑repair targeted strategies.
- Metastatic castration‑sensitive prostate cancer
- HRR gene‑mutated prostate cancer
- Metastatic castration‑resistant prostate cancer
Efforts aim to improve radiographic progression‑free survival and overall disease control.
Respiratory and Pulmonary Disease Management
Dedicated to advancing treatment for chronic obstructive pulmonary disease and severe eosinophilic asthma, with emphasis on reducing exacerbations and optimizing anti‑inflammatory therapy.
- Chronic obstructive pulmonary disease
- Severe eosinophilic asthma
- Exacerbation reduction therapies
Investigations include inhaled corticosteroid stewardship and biologic agents targeting eosinophilic pathways.
Orthopedic and Post‑Surgical Pain
Research addresses pain control and functional outcomes after hip and knee arthroplasty, management of osteoarthritis, and strategies for acute postoperative pain mitigation.
- Hip and knee arthroplasty
- Osteoarthritis
- Acute postoperative pain
Focus includes non‑opioid analgesic protocols and rehabilitation optimization.
Cardiovascular and Metabolic Outcomes
Investigations target secondary prevention after myocardial infarction, management of heart failure, and broader composite cardiovascular event reduction.
- Myocardial infarction
- Heart failure
- Cardiovascular event composite outcomes
Therapeutic approaches include beta‑blocker regimens and risk‑modifying interventions.
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