Angelica P.
- Country
- Italy
- Department
- UOC Medicina Interna e Immunologia Clinica
Research Overview
- A Phase 3b Long-term Efficacy and Safety Extension Study of Barzolvolimab in Participants with Chronic Spontaneous Urticaria
- Efficacy and Safety of Barzolvolimab in Patients with Chronic Spontaneous Urticaria Symptomatic Despite H1 Antihistamine Treatment: A Phase 3 Randomized, Placebo-Controlled Study
Data & Insights
Has run more than one trial at 65 of 158 partner sites.
Specializations
Allergic Rhinoconjunctivitis and Seasonal Ocular Allergy
The investigator concentrates on IgE‑driven inflammation of the nasal mucosa and conjunctiva, targeting pathways that drive seasonal symptom spikes.
- Allergic rhinoconjunctivitis
- Seasonal allergic conjunctivitis
- Allergic rhinitis
Research emphasizes biologic and immunomodulatory strategies to reduce type‑2 cytokine activity.
Atopic Dermatitis and Related Dermatologic Immunopathology
Work in this area addresses chronic skin inflammation driven by barrier dysfunction and immune dysregulation.
- Atopic dermatitis
- Moderate-to-severe plaque psoriasis
Efforts focus on therapeutic agents that restore skin homeostasis and attenuate Th2/Th17 signaling.
Primary Immunodeficiency and Immune Dysregulation
Investigations target congenital and acquired defects in humoral immunity, aiming to improve host defense and reduce autoimmunity.
- Primary immunodeficiency
- Common variable immunodeficiency
- Immunoglobulin replacement therapy
Studies explore optimal dosing regimens and novel formulations to enhance patient outcomes.
Autoimmune Neuromuscular and Systemic Disorders
This portfolio includes antibody‑mediated diseases affecting muscle and systemic autoimmunity.
- Generalized Myasthenia Gravis
- Lupus erythematosus
- Chronic spontaneous urticaria
Therapeutic focus is on targeted immunosuppression and modulation of pathogenic autoantibodies.
Chronic Respiratory Diseases with Immunologic Component
Research addresses airway diseases where immune pathways drive persistent inflammation and remodeling.
- Asthma
- Chronic obstructive pulmonary disease
Projects evaluate anti‑type‑2 agents and novel inhaled therapeutics to improve lung function.
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