Anette-Gabriele Z.
- Country
- Germany
- Department
- Institute of Diabetes Research
Research Overview
- Evaluation of Raxtozinameran Vaccination in Children with Elevated Genetic Risk for Type 1 Diabetes: Impact on Islet Autoantibody Incidence
- A Phase 2b, Randomised, Double-Blind, Placebo-Controlled, Parallel-Arm Dose Finding Study Evaluating the Efficacy and Safety of SAB-142 for Delaying the Progression of Type 1 Diabetes (T1D) in Patients with Stage 3 New Onset of Type 1 Diabetes (NOT1D)
Data & Insights
Has run more than one trial at 3 of 31 partner sites.
Specializations
Pediatric Diabetes Research
The investigator specializes in studying early interventions for children with elevated genetic risk for Type 1 diabetes, focusing on preventive strategies in pediatric populations. Their research explores the relationship between viral infections and autoimmune responses in diabetes development.
- Early-onset diabetes prevention
- Genetic risk assessment
- Childhood autoimmunity
Their work encompasses the study of islet autoantibodies and their development in young children, particularly examining immunological interventions starting from 6 months of age.
Immunological Studies
The investigator focuses on understanding the autoimmune mechanisms underlying Type 1 diabetes development, with particular attention to viral impacts on immune system responses in young children.
- Vaccination effects
- Immune system monitoring
- Autoantibody development
Their research examines the interplay between viral infections and autoimmune responses in the context of diabetes risk.
Preventive Medicine
The investigator examines innovative approaches to diabetes prevention, particularly focusing on early-life interventions in children with genetic predisposition to Type 1 diabetes.
- Risk factor modification
- Early intervention strategies
- Long-term disease prevention
Their work involves monitoring the cumulative incidence of diabetes-related autoimmunity in pediatric populations.
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