Andrés S. S.
- Country
- Spain
- Department
- Hematología
Research Overview
- A Study of Q702 in Patients with Relapsed or Refractory Chronic Graft-versus-Host Disease
- Phase I/IIa Study of Allogeneic Adipose-Derived Mesenchymal Stromal Cells Ectopically Expressing CXCR4 and IL-10 in Patients with Steroid- or Ruxolitinib-Refractory Acute GVHD
- Phase 2 Multicenter Trial of Mesenchymal Stromal Cells MC0518 vs. Best Available Therapy in Pediatric Steroid-Refractory Acute Graft-Versus-Host Disease
Data & Insights
Has run more than one trial at 60 of 148 partner sites.
Specializations
Hematologic Malignancies and Cellular Therapy
Clinical research activity centers on leukemia, lymphoma, and multiple myeloma, with interest in both relapsed and newly diagnosed disease. The portfolio also includes advanced approaches in immune-based therapy and cell therapy for aggressive blood cancers.
- Acute myeloid leukemia
- Acute lymphoblastic leukemia
- Diffuse large B-cell lymphoma
- Multiple myeloma
- Chronic lymphocytic leukemia
Research involvement extends across lymphoid and myeloid neoplasms, including studies of bispecific antibodies, CAR-T therapy, and other targeted hematology interventions.
Breast Cancer and Endocrine Oncology
The investigator shows strong involvement in breast cancer research, particularly hormone receptor-positive, HER2-negative, HER2-positive, and triple-negative breast cancer. The therapeutic focus includes targeted treatment, endocrine therapy, and adjuvant and neoadjuvant oncology.
- Hormone receptor-positive breast cancer
- HER2-positive breast cancer
- Triple-negative breast cancer
- Early breast cancer
- Metastatic breast cancer
Research themes also include PI3K-pathway targeting, PARP inhibition, and treatment strategies for advanced and high-risk breast neoplasms.
Cardiovascular Medicine and Thromboembolic Disease
Clinical work is strongly oriented toward cardiovascular disease, with emphasis on heart failure, myocardial infarction, atrial fibrillation, and atherosclerotic cardiovascular disease. The therapeutic scope includes prevention of stroke and management of high cardiovascular risk states.
- Heart failure
- Acute myocardial infarction
- Atrial fibrillation
- Atherosclerotic cardiovascular disease
- Hypertrophic cardiomyopathy
Additional activity includes cardiometabolic risk reduction, antithrombotic therapy, and studies in amyloid cardiomyopathy and resistant hypertension.
Autoimmune, Inflammatory, and Neurologic Disorders
The investigator is involved in therapeutic research for multiple sclerosis, systemic lupus erythematosus, inflammatory bowel disease, and related immune-mediated conditions. This includes interest in both neurologic and gastroenterologic inflammatory disease.
- Multiple sclerosis
- Systemic lupus erythematosus
- Crohn’s disease
- Ulcerative colitis
- Chronic graft-versus-host disease
Research also spans immune thrombocytopenia, myelin oligodendrocyte glycoprotein antibody-associated disease, and other chronic autoimmune and inflammatory syndromes.
Rare Diseases, Solid Tumors, and Hematologic Supportive Care
Additional trial involvement covers a broad range of solid tumors, including ovarian cancer, lung cancer, melanoma, prostate cancer, and endometrial cancer. The portfolio also includes rare hematologic disorders and supportive treatment areas.
- Ovarian cancer
- Non-small cell lung cancer
- Melanoma
- Hemophilia
- Thalassemia
Therapeutic interest extends to targeted oncology, precision medicine, and disease areas such as cardiomyopathy, chronic kidney disease, and metabolic disorders.
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