Andreas P.
- Country
- Austria
- Department
- Department of Clinical Pharmacology
Research Overview
- Evaluation of Chemotherapy Regimens Including Cisplatin, Cyclophosphamide, and Etoposide in Pediatric and Young Adult Ependymoma Treatment
- Evaluation of Hyperfractionated-Accelerated Radiotherapy and High-Dose Thiotepa Therapy in High-Risk Medulloblastoma Patients Aged Over 3 Years
- Evaluation of Carboplatin and Chemotherapeutic Regimen in Pediatric Patients with Standard-Risk and High-Risk Medulloblastoma: A Multinational Prospective Study
Data & Insights
Has run more than one trial at 128 of 169 partner sites.
Specializations
Neuro-Oncology
The investigator specializes in treating pediatric brain tumors, with particular emphasis on medulloblastoma and ependymoma. Their expertise extends to various tumor subtypes including sonic hedgehog (SHH) and non-wingless-type (WNT) variants.
- High-risk medulloblastoma management
- Ependymoma treatment protocols
- Atypical teratoid rhabdoid tumors
Their work encompasses both standard-risk and high-risk disease classifications.
Treatment Approaches
The investigator focuses on developing multi-modal treatment strategies, incorporating radiotherapy innovations and metronomic anti-angiogenic therapies. Their work includes evaluation of different radiation protocols and maintenance chemotherapy regimens.
- Hyperfractionated-accelerated radiotherapy
- High-dose therapy protocols
- Anti-angiogenic treatments
The research includes assessment of novel therapeutic combinations for improved patient outcomes.
Clinical Pharmacology
The investigator studies antibiotic pharmacokinetics in the context of brain tumors, with particular focus on cerebrospinal fluid penetration and distribution in patients with leptomeningeal disease.
- CSF drug concentration analysis
- Antibiotic administration protocols
- CNS drug distribution studies
Their research examines both intravenous and oral medication administration routes.
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