Andrea E.
- Country
- Germany
- Department
- MVZ fuer Rheumatologie und Autoimmunmedizin Hamburg GmbH
Research Overview
- Evaluation of Dazodalibep Efficacy and Safety in Patients with Moderate-to-Severe Sjögren’s Syndrome: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study
- Efficacy and Safety Evaluation of Dazodalibep in Patients with Moderate-to-Severe Systemic Sjögren’s Syndrome: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study
- 22104: A Randomized, Double-blind, Placebo-controlled, Multicenter Phase 2b/3 Study to Evaluate the Efficacy and Safety of Izokibep in Subjects with Active Psoriatic Arthritis
Data & Insights
Has run more than one trial at 379 of 771 partner sites.
Specializations
Rheumatoid arthritis and autoimmune inflammatory disease
Andrea Everding’s clinical trial activity is centered on rheumatoid arthritis, with involvement in treatment strategies for moderate to severe disease, ACPA-positive rheumatoid arthritis, and early seropositive disease. The research landscape also includes therapies for patients with inadequate response to prior methotrexate or TNF inhibitor treatment.
- Moderate to severe rheumatoid arthritis
- ACPA-positive rheumatoid arthritis
- Early seropositive rheumatoid arthritis
- Post-treatment inadequate response in RA
This work spans targeted immunomodulatory therapies and treatment approaches aimed at controlling joint inflammation and preserving function.
Psoriatic arthritis and axial spondyloarthritis
Another major focus is inflammatory musculoskeletal disease, particularly psoriatic arthritis and axial spondyloarthritis, including radiographic and non-radiographic forms. The clinical portfolio reflects interest in symptom control, disease activity reduction, and longer-term management of chronic spondyloarthritic conditions.
- Active psoriatic arthritis
- Radiographic axial spondyloarthritis
- Non-radiographic axial spondyloarthritis
- Axial spondyloarthritis with prior biologic exposure
The therapeutic emphasis includes biologic and small-molecule approaches for inflammatory arthritis across multiple patient subgroups.
Sjögren’s disease and systemic autoimmune syndromes
Andrea Everding is actively involved in trials addressing Sjögren’s disease and Sjögren’s syndrome, including forms with moderate-to-severe systemic disease activity and persistent symptom burden. The research scope extends to therapies intended to improve systemic manifestations and patient-reported symptoms in autoimmune exocrinopathy.
- Primary Sjögren’s disease
- Moderate to severe Sjögren’s syndrome
- Systemic disease activity in Sjögren’s disease
- Symptom-focused Sjögren’s syndrome treatment
This area highlights interest in systemic autoimmune disease and therapies targeting broader immune-mediated organ involvement.
Musculoskeletal pain and osteoarthritis
The investigator also contributes to studies in osteoarthritis and chronic pain conditions, with particular attention to knee osteoarthritis pain and chronic peripheral neuropathic pain. These trials reflect a therapeutic interest in symptom relief and functional improvement in degenerative and pain-driven disorders.
- Knee osteoarthritis pain
- Osteoarthritis
- Chronic peripheral neuropathic pain
- Polymyalgia rheumatica
The portfolio includes anti-inflammatory and analgesic treatment domains relevant to chronic rheumatologic and pain syndromes.
Cardiometabolic, infectious, and neurodegenerative conditions
Beyond rheumatology, the clinical research profile includes selected studies in atherosclerotic cardiovascular disease, elevated Lp(a), overweight or obesity, COVID-19, and early symptomatic Alzheimer’s disease. These areas indicate engagement with broader therapeutic domains that intersect prevention, chronic disease risk, and progressive neurologic illness.
- Atherosclerotic cardiovascular disease
- Elevated Lp(a)
- Overweight or obesity
- Early symptomatic Alzheimer’s disease
The trial portfolio shows involvement in cardiometabolic, infectious disease, and neurology research alongside immune-mediated disease programs.
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