Anamaria Ioana S.
- Country
- France
- Department
- Pediatric Hematology
Research Overview
- Asciminib in Pediatric Philadelphia-Positive Chronic Myeloid Leukemia in Chronic Phase With or Without T315I Mutation: Phase II Safety and Efficacy Study
- Phase II Randomized Controlled Trial of Trametinib vs. Vinblastine in Pediatric and AYA Patients with Newly Diagnosed Low-Grade Glioma with Wild-Type BRAF
- ALLTogether1 - A Treatment Study Protocol of the ALLTogether Consortium for Children and Young Adults (0-45 Years of Age) with Newly Diagnosed Acute Lymphoblastic Leukaemia (ALL)
Data & Insights
Has run more than one trial at 100 of 217 partner sites.
Specializations
Oncology and solid tumor therapeutics
Clinical research activity includes a broad range of solid malignancies, with particular interest in gastrointestinal cancers, breast cancer, lung cancer, gastroesophageal cancer, hepatocellular carcinoma, renal cell carcinoma, ovarian cancer, and sarcomas.
- Metastatic colorectal cancer
- Advanced non-small cell lung cancer
- HER2-positive and hormone receptor-positive breast cancer
- Gastric, esophageal, and biliary tract cancers
- Soft tissue sarcoma and rare sarcoma subtypes
The therapeutic scope also extends to neuroendocrine tumors, urothelial carcinoma, pancreatic cancer, melanoma, and head and neck squamous cell carcinoma.
Hematology and blood cancer care
Research interests cover malignant and non-malignant hematologic disorders, with activity in acute leukemia, lymphoma, multiple myeloma, myelodysplastic syndromes, myelofibrosis, and plasma cell dyscrasias.
- Acute lymphoblastic leukemia and acute myeloid leukemia
- Diffuse large B-cell lymphoma and follicular lymphoma
- Multiple myeloma and Waldenström macroglobulinemia
- Myelodysplastic syndrome and myelofibrosis
- Immune thrombocytopenia and thrombotic complications
Additional focus includes post-transplant hematologic complications, high-risk leukemia, and cell therapy-related follow-up.
Cardiovascular, thrombotic, and metabolic disease
Investigational work spans acute coronary syndromes, myocardial infarction, stroke, heart failure, atrial fibrillation, and broader atherosclerotic cardiovascular disease.
- Acute ischemic stroke and transient ischemic attack
- Heart failure and cardiomyopathy
- Atrial fibrillation and cardioembolic prevention
- Hypertension, hyperkalemia, and type 2 diabetes
- Venous thromboembolism and antithrombotic therapy
Related interests include valvular heart disease, cardiovascular risk reduction, and acute cardiac care.
Autoimmune, inflammatory, and renal disorders
The investigator is involved in studies of systemic autoimmune disease, vasculitis, arthritis, lupus, and kidney disease, reflecting interest in chronic immune-mediated conditions and organ-specific complications.
- Systemic lupus erythematosus and lupus nephritis
- Rheumatoid arthritis and juvenile idiopathic arthritis
- ANCA-associated vasculitis and giant cell arteritis
- Chronic kidney disease and kidney transplantation
- Pulmonary arterial hypertension and interstitial lung disease
Other areas include primary biliary cholangitis, Crohn’s disease, hidradenitis suppurativa, and systemic sclerosis.
Infectious disease, critical care, and perioperative medicine
Clinical trial involvement also covers severe infection, sepsis, pneumonia, ICU care, and surgical prophylaxis, alongside acute management of respiratory and neurologic emergencies.
- Sepsis and septic shock
- Hospital-acquired pneumonia and ventilator-associated pneumonia
- Severe influenza and COVID-19
- Postoperative critical care and surgical antibiotic prophylaxis
- Hemoptysis and bacterial brain abscess
Additional interests include transplant-related infection, acute myocarditis, and neurologic intensive care.
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