Ana Laura F. P.
- Country
- Spain
- Department
- Epilepsy
Research Overview
- Efficacy and Safety of Fenfluramine Hydrochloride in Pediatric and Adult Patients with CDKL5 Deficiency Disorder: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study
- Evaluation of Long-Term Safety and Efficacy of Bexicaserin (LP352) in Pediatric and Adult Patients with Developmental and Epileptic Encephalopathy
Data & Insights
Has run more than one trial at 12 of 46 partner sites.
Specializations
Epilepsy and Seizure Disorders
Investigator concentrates on developmental and epileptic encephalopathies, focal seizures, and primary generalized tonic‑clonic seizures across pediatric and adult cohorts.
- Focal seizure frequency
- Primary generalized tonic‑clonic seizures
- Developmental and epileptic encephalopathies
- Dravet syndrome
- Tuberous sclerosis complex
Efforts emphasize novel antiseizure agents and comprehensive safety profiling.
Respiratory and Pulmonary Conditions
Investigator addresses asthma management and exacerbation control.
Research also targets idiopathic pulmonary fibrosis through cough frequency reduction and long‑term safety evaluation.
- Asthma exacerbations
- Cough frequency in IPF
- Long‑term safety of inhaled therapies
Digital monitoring tools are integrated to quantify respiratory outcomes.
Cardiovascular and Thrombotic Diseases
Investigator explores atrial fibrillation therapeutics.
Focus includes primary prevention of atherosclerotic cardiovascular disease.
Studies also target venous thromboembolism in cancer settings.
- Atrial fibrillation risk reduction
- Major adverse cardiovascular events
- Cancer‑associated VTE recurrence
- Primary prevention of ASCVD
Emphasis is placed on anticoagulation alternatives and lipid‑lowering strategies.
Oncology and Targeted Therapies
Investigator contributes to non‑small cell lung cancer trials.
Research also includes head and neck squamous cell carcinoma immunotherapy.
- Metastatic non‑squamous NSCLC
- PD‑L1‑positive head and neck cancer
- ROS1‑positive NSCLC with brain metastasis
- Novel immunotherapy combinations
Assessments focus on objective response rates and durable tumor control.
Pediatric Rheumatology and Neurodegeneration
Investigator investigates systemic juvenile idiopathic arthritis pharmacokinetics.
Studies also address cognitive decline in Parkinson’s disease.
- Systemic juvenile idiopathic arthritis
- Parkinson’s disease cognitive impairment
- Mild cognitive impairment
- Pediatric pharmacokinetic profiling
Efforts aim to optimize dosing and therapeutic outcomes in young patients.
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