Amparo S. G.
- Country
- Spain
- Department
- Servicio de Oncología
Research Overview
- Evaluation of STX-721 in Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring Specific Mutations
- A Phase II Study of IBI3009 Monotherapy or in Combination with Combination Therapy in Patients with Extensive-Stage Small Cell Lung Cancer
- Phase 3 Randomized Open‑Label Study of ZL‑1310 versus Investigator‑Chosen Topotecan in Relapsed Small Cell Lung Cancer
Data & Insights
Has run more than one trial at 93 of 287 partner sites.
Specializations
Breast Cancer and Solid Tumor Oncology
Clinical research activity is strongly centered on breast cancer, with involvement in hormone receptor-positive, HER2-negative, HER2-positive, triple-negative breast cancer, and advanced metastatic disease. The portfolio also extends across broader solid tumor settings, including lung cancer, ovarian cancer, prostate cancer, renal cell carcinoma, and urothelial carcinoma.
- Metastatic breast cancer
- Advanced non-small cell lung cancer
- Renal cell carcinoma
- Urothelial carcinoma
There is a clear therapeutic focus on precision oncology, brain metastases, and treatment strategies for refractory or locally advanced malignancies.
Hematologic Malignancies and Cellular Therapy
The investigator is actively involved in studies of acute leukemia, myelodysplastic syndromes, multiple myeloma, and multiple lymphoma subtypes, including diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, and chronic lymphocytic leukemia. Research also includes CAR T-cell therapy and other advanced immuno-oncology approaches.
- Acute myeloid leukemia
- Multiple myeloma
- Diffuse large B-cell lymphoma
- CAR T-cell therapy
Additional interest is evident in relapsed and refractory hematologic disease, with attention to innovative treatment options for difficult-to-treat blood cancers.
Respiratory, Thoracic, and Inflammatory Lung Disease
Clinical trial involvement includes a broad spectrum of lung cancer indications alongside non-malignant respiratory conditions such as asthma, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, progressive pulmonary fibrosis, pulmonary sarcoidosis, and bronchiectasis. The research landscape also covers pulmonary hypertension and other chronic thoracic disorders.
- Non-small cell lung cancer
- Small cell lung cancer
- Idiopathic pulmonary fibrosis
- Pulmonary sarcoidosis
Therapeutic interest spans both oncologic and non-oncologic pulmonary disease, including conditions associated with fibrosis and chronic respiratory impairment.
Autoimmune, Inflammatory, and Gastrointestinal Disorders
The investigator participates in studies addressing systemic lupus erythematosus, psoriatic arthritis, Behçet’s disease, ulcerative colitis, Crohn’s disease, and primary biliary cholangitis. This area also includes atopic dermatitis, alopecia-related inflammatory disease, and other immune-mediated conditions.
- Systemic lupus erythematosus
- Crohn’s disease
- Ulcerative colitis
- Primary biliary cholangitis
Research activity reflects interest in immune-mediated inflammation and chronic gastrointestinal disease, with therapeutic attention to symptom control and disease modification.
Cardiometabolic, Neurologic, and Renal Disease
Additional trial involvement includes cardiovascular disease, heart failure, atrial fibrillation, atherosclerotic cardiovascular disease, and obesity-related metabolic disease. The portfolio also covers migraine, Parkinson’s disease, schizophrenia, Alzheimer’s disease, and kidney disorders such as chronic kidney disease, IgA nephropathy, and glomerular disease.
- Atherosclerotic cardiovascular disease
- Chronic kidney disease
- Migraine
- Parkinson’s disease
There is also involvement in metabolic liver disease, type 2 diabetes, and other chronic disorders that intersect with long-term internal medicine and supportive care.
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