Amina T.
- Country
- France
- Department
- oncologie médicale
Research Overview
Data & Insights
Has run more than one trial at 0 of 18 partner sites.
Specializations
Thoracic Oncology
Investigates therapeutic strategies for Non‑Small Cell Lung Cancer across stages and molecular subtypes.
- Adjuvant immunotherapy in resected disease
- Targeted agents for ROS1‑positive and HER2‑mutated tumors
- Combination regimens for advanced disease
Clinical activities are coordinated through the Groupe Hospitalier De La Région De Mulhouse Et Sud Alsace.
Hematologic Malignancies
Focuses on innovative treatments for acute leukemias and lymphoid neoplasms.
- Frontline incorporation of blinatumomab in Acute Lymphoblastic Leukemia
- Targeted therapy for Acute Myeloid Leukemia with NPM1‑mut or KMT2A‑r
- Bispecific antibodies and CAR‑T approaches in relapsed Diffuse Large B‑Cell Lymphoma
Efforts aim to improve remission depth and long‑term survival.
Renal and Cardiovascular Therapeutics
Addresses disease mechanisms and outcomes in chronic kidney and vascular disorders.
- Low‑dose anticoagulation to reduce major adverse cardiovascular events in advanced Chronic Kidney Disease
- Diuretic‑based algorithms for uncontrolled hypertension in renal impairment
- Evaluation of novel agents for proteinuric kidney disease
Research integrates cardiology and nephrology perspectives.
Autoimmune and Glomerular Diseases
Explores immunomodulatory approaches for systemic and renal autoimmunity.
- Therapeutic withdrawal strategies in ANCA‑associated vasculitis
- Targeted treatment of Sjögren’s syndrome with moderate‑to‑severe activity
- Interventions for systemic lupus erythematosus renal involvement
Goals include reducing disease flares while preserving organ function.
Molecularly Targeted Oncology
Develops precision therapies for cancers driven by specific genetic alterations.
- KRAS‑directed inhibitors in KRAS G12C‑mutated lung cancer
- BRAF‑targeted combinations for BRAFV600E‑mutant tumors
- HER2‑focused agents in HER2‑mutated non‑small cell lung cancer
Efforts align with emerging biomarker‑driven treatment paradigms.
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