Alix R.
- Country
- France
- Department
- Memory center for Resources and Research
Research Overview
- Open-Label Long-Term Safety and Tolerability of ML-007C-MA (fesoterodine) in Adults with Hallucinations and Delusions of Alzheimer’s Disease Psychosis
- Long-term Safety and Tolerability Evaluation of Trospium Chloride and Xanomeline Tartrate in Agitation Associated with Alzheimer's Disease
- Evaluation of the Efficacy and Safety of Xanomeline Tartrate and Trospium Chloride in Cognitive Impairment Associated with Mild to Moderate Alzheimer's Disease
Data & Insights
Has run more than one trial at 128 of 198 partner sites.
Specializations
Neurology and Neurodegenerative Disease
Clinical activity includes studies in Alzheimer’s disease, mild cognitive impairment, Parkinson’s disease, multiple sclerosis, epilepsy, and dementia with Lewy bodies, with interest in cognitive decline, neuroinflammation, and progressive neurological disability.
- Alzheimer’s disease and cognitive impairment
- Multiple sclerosis and demyelinating disorders
- Epilepsy and seizure disorders
- Parkinson’s disease and movement disorders
Also involved in neurodevelopmental disorders, headache, and other central nervous system conditions.
Autoimmune and Inflammatory Diseases
Research spans systemic lupus erythematosus, lupus nephritis, rheumatoid arthritis, Sjögren’s syndrome, systemic sclerosis, idiopathic inflammatory myopathies, and vasculitis, reflecting a strong focus on immune-mediated disease.
- Systemic lupus erythematosus and lupus nephritis
- Sjögren’s syndrome
- Rheumatoid arthritis
- Vasculitis and myositis
Additional interests include sarcoidosis, antibody-mediated neuropathies, and other systemic autoimmune rheumatic diseases.
Hematology, Transplantation, and Cell Therapy
Clinical trial involvement covers acute leukemia, lymphoma, myelodysplastic syndromes, multiple myeloma, graft-versus-host disease, and hematopoietic stem cell transplantation, with attention to high-risk blood cancers and post-transplant complications.
- Acute lymphoblastic leukemia and acute myeloid leukemia
- Lymphoma and multiple myeloma
- Allogeneic hematopoietic stem cell transplantation
- Graft-versus-host disease
Also active in cell-based immunotherapy and transplant-associated hematologic disorders.
Thoracic, Renal, and Genitourinary Oncology
The oncology portfolio is centered on non-small cell lung cancer, renal cell carcinoma, urothelial carcinoma, prostate cancer, and hepatocellular carcinoma, with interest in advanced and metastatic solid tumors.
- Non-small cell lung cancer
- Renal cell carcinoma
- Urothelial carcinoma
- Prostate cancer and hepatocellular carcinoma
Further involvement extends to ovarian cancer, sarcoma, and other molecularly selected solid tumors.
Critical Care, Infectious Disease, and Cardiovascular Medicine
Additional trial activity includes sepsis, acute respiratory failure, pneumonia, influenza, tuberculosis, and fungal infections, alongside cardiovascular studies in heart failure, stroke, acute coronary syndrome, and thromboembolic disease.
- Sepsis and intensive care
- Respiratory infections and pulmonary disease
- Stroke and coronary disease
- Heart failure and thromboembolism
Also involved in kidney injury, chronic kidney disease, and other multisystem acute care conditions.
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