Alfonso B.
- Country
- Spain
- Department
- Oncology
Research Overview
- Long-term Safety Evaluation of Nivolumab Monotherapy or in Combination with Other Cancer Therapies in Patients with Pan Tumor Conditions
- Phase 2 Randomized Controlled Study of Cemiplimab Monotherapy and Cemiplimab Plus Vusolimogene Oderparepvec in Advanced Cutaneous Squamous Cell Carcinoma
- Phase 2/3 Study of Darovasertib and Crizotinib Versus Standard Treatment in HLA-A2 Negative Metastatic Uveal Melanoma
Data & Insights
Has run more than one trial at 64 of 199 partner sites.
Specializations
Solid Tumor Oncology
The investigator’s work centers on therapeutic strategies for solid malignancies across multiple organ systems.
- Non‑Small Cell Lung Cancer
- Breast Cancer
- Colorectal Cancer
- Melanoma
- Ovarian Cancer
Clinical efforts emphasize targeted agents and immunotherapies for these tumor types.
Hepatology and Metabolic Liver Disease
Research activities include innovative treatments for chronic liver conditions such as non‑alcoholic steatohepatitis and hepatocellular carcinoma.
- Non‑Alcoholic Steatohepatitis (NASH)
- Hepatocellular Carcinoma
- Alcohol‑Related Liver Disease
- Chronic Hepatitis B
- Chronic Hepatitis C
These projects target metabolic pathways and fibrotic progression in the liver.
Hematologic Malignancies
Focus is placed on therapeutic advances for blood‑derived cancers, notably acute myeloid leukemia and related disorders.
- Acute Myeloid Leukemia
- Diffuse Large B‑Cell Lymphoma
- Multiple Myeloma
- Myelofibrosis
- Chronic Lymphocytic Leukemia
Clinical programs explore novel agents and combination regimens for these hematologic diseases.
Dermatologic and Immune‑Mediated Disorders
Investigations extend to inflammatory skin conditions, including atopic dermatitis and chronic urticaria.
- Atopic Dermatitis
- Chronic Spontaneous Urticaria
- Psoriatic Arthritis
- Alopecia Areata
- Cutaneous Lupus Erythematosus
Efforts aim to define disease‑modifying pathways and biologic interventions for these immune‑mediated conditions.
Cardiovascular and Metabolic Disorders
The investigator contributes to studies addressing major cardiovascular diseases and metabolic risk factors.
- Atrial Fibrillation
- Acute Coronary Syndrome
- Obesity
- Type 2 Diabetes Mellitus
- Heart Failure
These projects evaluate preventive and therapeutic approaches for cardio‑metabolic health.
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