Alexík M.
- Country
- Slovakia
- Department
- NA
Research Overview
- Phase 2 Double-Masked Placebo-Controlled Dose-Finding Study of Danicopan in Geographic Atrophy Secondary to Age-Related Macular Degeneration
- Phase 3 Randomized Study Comparing Efficacy and Safety of BP05 and Ranibizumab in Patients with Neovascular Age-Related Macular Degeneration
- Phase 3 Trial Comparing Efficacy, Safety, and Immunogenicity of Aflibercept (RBS-001) Versus Aflibercept in Neovascular Age-Related Macular Degeneration
Data & Insights
Has run more than one trial at 1 of 79 partner sites.
Specializations
Retinal vascular and macular disease
Clinical research activity is centered on diabetic macular edema, neovascular age-related macular degeneration, and geographic atrophy secondary to age-related macular degeneration. The therapeutic focus includes vision preservation, macular anatomy, and comparative effectiveness of intravitreal treatments.
- Diabetic macular edema
- Wet age-related macular degeneration
- Geographic atrophy
- Intravitreal anti-VEGF therapy
Interest also extends to treatment burden, visual acuity outcomes, and longer-term retinal disease management.
Neurovascular and cerebrovascular disorders
The investigator is involved in studies of acute ischemic stroke and high-risk transient ischemic attack, reflecting a therapeutic emphasis on prevention of recurrent ischemic events and vascular protection.
- Acute ischemic stroke
- Transient ischemic attack
- Antithrombotic therapy
These activities align with clinical interest in reducing cerebrovascular risk and improving post-event outcomes.
Infectious disease and diabetic foot complications
Research involvement includes diabetic foot infections and antibacterial treatment evaluation, indicating attention to complex soft-tissue and limb-threatening infections in people with diabetes.
- Diabetic foot infections
- Antibacterial therapy
- Severe diabetic complications
The therapeutic domain includes infection control, clinical response assessment, and preservation of limb function.
Oncology
Clinical trial participation spans several cancer settings, including hormone receptor-positive, HER2-negative advanced/metastatic breast cancer, prostate cancer, and stage IV non-squamous non-small cell lung cancer. The focus is on systemic anticancer therapy and disease control in advanced malignancy.
- Advanced/metastatic breast cancer
- Prostate cancer
- Non-small cell lung cancer
- Endocrine-based cancer therapy
These studies reflect involvement in targeted treatment strategies and maintenance of benefit in chronic oncology care.
Neurology and chronic immune-mediated disease
The investigator also contributes to research in multiple sclerosis, with additional exposure to long-term safety evaluation of disease-modifying therapy in chronic neurologic disease.
- Multiple sclerosis
- Long-term immunotherapy safety
This area complements a broader interest in sustained treatment benefit and monitoring in progressive or relapsing neurologic conditions.
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