Alexia R.
- Country
- France
- Department
- Endocrinology, Diabetes and Metabolic Diseases
Research Overview
- Effect of Muvalaplin on Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) and Atherosclerotic Cardiovascular Disease: A Phase 3 Randomized Trial
- Phase 3 Evaluation of Pegozafermin Efficacy and Safety in Metabolic Dysfunction-Associated Steatohepatitis with Compensated Cirrhosis
Data & Insights
Has run more than one trial at 22 of 297 partner sites.
Specializations
Endocrinology and Diabetology
- Type 1 diabetes mellitus
- Type 2 diabetes mellitus
- Diabetic macular edema
- Atherosclerotic cardiovascular disease
Work also extends to obesity, hypertriglyceridemia, and cardiometabolic prevention strategies.
Cardiovascular and Thromboembolic Disease
Active involvement in studies of heart failure, atrial fibrillation, acute coronary syndrome, myocardial infarction, and broader cardiovascular disease.
- Heart failure
- Atrial fibrillation
- Venous thromboembolism
- Stroke prevention
Additional therapeutic interest includes atherosclerosis, cardiogenic shock, and prevention of major cardiovascular events.
Autoimmune and Inflammatory Disorders
Research activity includes giant cell arteritis, polymyalgia rheumatica, ANCA-associated vasculitis, systemic sclerosis, and immune thrombocytopenia.
- Giant cell arteritis
- Polymyalgia rheumatica
- Systemic sclerosis
- Immune thrombocytopenia
Therapeutic interests also cover Crohn's disease, ulcerative colitis, psoriasis, and other immune-mediated conditions.
Ophthalmology and Retinal Disease
Clinical trial involvement includes diabetic macular edema, neovascular age-related macular degeneration, geographic atrophy, and glaucoma.
- Diabetic macular edema
- Neovascular age-related macular degeneration
- Geographic atrophy
- Glaucoma
Interest also extends to visual outcomes in macular disease and retinal vascular disorders.
Oncology and Hematologic Malignancies
Research spans colorectal cancer, non-small cell lung cancer, biliary tract cancer, and multiple hematologic cancers including lymphoma and multiple myeloma.
- Colorectal cancer
- Non-small cell lung cancer
- Lymphoma
- Multiple myeloma
Therapeutic interest also includes melanoma, pancreatic cancer, and neuroendocrine tumors.
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