Alexandra F.
- Country
- Czechia
- Department
- Dermatovenerology
Research Overview
- A Phase 2, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of BFB759 in Patients with Moderate to Severe Hidradenitis Suppurativa
- Phase 2 Randomized, Double-Blind, Placebo-Controlled Study of LY4100511 in Adults with Moderate-to-Severe Plaque Psoriasis
- A Phase 2b, Multicenter, Randomized, Double-blinded, Placebo-controlled, Parallel-group, Dose-finding Study to Evaluate the Efficacy and Safety of IMG-007 in Adult Participants with Moderate-to-Severe Atopic Dermatitis
Data & Insights
Has run more than one trial at 17 of 78 partner sites.
Specializations
Inflammatory skin disease
Clinical activity centers on atopic dermatitis, plaque psoriasis, hidradenitis suppurativa, and alopecia areata, with additional involvement in related dermatoses such as eczema and dermatitis.
- Atopic dermatitis
- Plaque psoriasis
- Hidradenitis suppurativa
- Alopecia areata
Research interests include targeted approaches for persistent inflammatory skin disorders and symptom control in chronic cutaneous disease.
Psoriatic and rheumatologic disease
The investigator is engaged in trials for psoriatic arthritis, rheumatoid arthritis, and axial spondyloarthritis, reflecting a strong focus on immune-mediated musculoskeletal disease.
- Psoriatic arthritis
- Rheumatoid arthritis
- Axial spondyloarthritis
- Moderately to severely active rheumatologic disease
Her work also extends to treatment-resistant inflammatory joint disease and overlap syndromes linking skin and joint involvement.
Musculoskeletal pain and osteoarthritis
Another area of interest is knee osteoarthritis and chronic pain, including chronic non-specific low back pain and pain-related functional limitation in degenerative joint disease.
- Knee osteoarthritis
- Chronic pain
- Chronic non-specific low back pain
- Osteoarthritis
Trial involvement in this domain highlights interest in therapies aimed at improving pain relief and mobility in chronic musculoskeletal conditions.
Cardiometabolic disease
Her clinical research landscape includes atherosclerotic cardiovascular disease, elevated LDL-C, elevated lipoprotein(a), obesity, overweight, and type 2 diabetes.
- Atherosclerotic cardiovascular disease
- Elevated LDL-C
- Obesity
- Type 2 diabetes
These studies reflect therapeutic interest in cardiometabolic risk reduction and long-term disease prevention.
Neurologic and metabolic symptom control
Additional involvement includes migraine prevention and chronic weight management, alongside gout with hyperuricemia, expanding the investigator’s scope into symptom-focused and metabolic care.
- Chronic and episodic migraine
- Chronic weight management
- Gout with hyperuricemia
- Obesity or overweight
This portfolio includes therapeutic areas where sustained control of chronic symptoms and metabolic burden remains clinically important.
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