Alejandra C.
- Country
- Spain
- Department
- Oncology
Research Overview
- Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Patients With Previously Treated TROP2-Positive Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
- Evaluation of Adagrasib Dosing Regimens in Previously Treated KRAS G12C-Mutant Non-Small Cell Lung Cancer Patients
- Phase 3 Study of Trastuzumab Deruxtecan vs. Platinum-Based Chemotherapy in HER2-Mutant Unresectable or Metastatic NSCLC
Data & Insights
Has run more than one trial at 95 of 252 partner sites.
Specializations
Thoracic Oncology and Targeted Cancer Therapy
Clinical research activity is strongly centered on non-small cell lung cancer, small cell lung cancer, and other advanced solid tumours, with interest in biomarker-defined disease and treatment-resistant malignancies.
- EGFR-mutated NSCLC
- ALK-positive and ROS1-positive lung cancer
- Metastatic colorectal cancer
- Pancreatic ductal adenocarcinoma
Her oncology portfolio also includes melanoma, head and neck squamous cell carcinoma, gastroesophageal adenocarcinoma, and urothelial carcinoma.
Immuno-Oncology and Advanced Solid Tumors
Her trial involvement reflects a focus on immune-based treatment strategies across metastatic and locally advanced cancers, especially in settings where resistance or recurrence remains a major clinical issue.
- Immune checkpoint inhibition
- Combination immunotherapy
- HER2-positive and HER2-negative breast cancer
- Endometrial cancer
She is also involved in research on triple-negative breast cancer, gastric cancer, and colorectal cancer with molecularly selected treatment approaches.
Neuroinflammatory and Neurological Disorders
Her research landscape includes diseases of the central nervous system and neuromuscular junction, with attention to chronic inflammatory and relapsing neurologic conditions.
- Multiple sclerosis
- Myasthenia gravis
- Amyotrophic lateral sclerosis
- Epilepsy
Additional interest is seen in Parkinson’s disease, developmental and epileptic encephalopathies, and tuberous sclerosis complex-related epilepsy.
Autoimmune, Inflammatory, and Rare Immune-Mediated Diseases
She is active in trials for systemic and organ-specific immune disorders, spanning both chronic inflammatory disease and rare antibody-mediated conditions.
- Rheumatoid arthritis
- Psoriatic arthritis
- Systemic lupus erythematosus
- Systemic sclerosis
Her portfolio also includes Crohn’s disease, ulcerative colitis, bullous pemphigoid, and chronic spontaneous urticaria.
Hematology, Transplantation, and Inherited Blood Disorders
Her clinical research extends to hematologic malignancies, transplant-related complications, and coagulation disorders, highlighting a broad interest in supportive and disease-modifying therapies.
- Acute myeloid leukemia
- Multiple myeloma
- Hemophilia A and hemophilia B
- Graft-versus-host disease
She also contributes to studies in myelodysplastic syndromes, lymphoma, and kidney transplant rejection.
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