Alex G. D.
- Country
- Spain
- Department
- Nephrology
Research Overview
- Evaluation of Autologous Tolerogenic Dendritic Cells in Highly Sensitized Patients Undergoing Kidney Transplantation
- Phase 2 Study of Empasiprubart in Deceased Donor Renal Allograft Recipients at Risk for Delayed Graft Function
- Phase 2 Randomized, Double-Blind, Placebo-Controlled Study of Efgartigimod Alfa SC in Antibody-Mediated Rejection in Kidney Transplant Recipients
Data & Insights
Has run more than one trial at 23 of 56 partner sites.
Specializations
Kidney Disease and Transplantation
Alex Gutiérrez is involved in clinical research centered on nephrology, with a strong focus on IgA nephropathy, lupus nephritis, focal segmental glomerulosclerosis, and end-stage renal disease. The research landscape also includes kidney transplantation, antibody-mediated rejection, delayed graft function, and graft-related complications.
- IgA nephropathy
- Lupus nephritis
- Kidney transplantation
- Antibody-mediated rejection
- Delayed graft function
His trial activity reflects interest in renal immunology, transplant preservation, and treatment strategies for chronic kidney injury.
Cardiovascular Risk and Metabolic Disorders
His clinical trial portfolio includes atherosclerotic cardiovascular disease, coronary artery disease, hypercholesterolemia, hypertriglyceridemia, and lipoprotein(a)-related risk. Additional activity covers thrombotic prevention, stroke prevention, and inherited or high-risk cardiovascular conditions.
- Atherosclerotic cardiovascular disease
- Coronary artery disease
- Hypercholesterolemia
- Hypertriglyceridemia
- Lipoprotein(a)
This area also extends to cardiometabolic prevention in patients with elevated vascular risk and systemic inflammatory burden.
Hepatology and Digestive Disease
Alex Gutiérrez is active in studies of primary biliary cholangitis, primary sclerosing cholangitis, non-alcoholic steatohepatitis, liver cirrhosis, and hepatic encephalopathy. His research interests also include portal hypertension, cholestatic pruritus, chronic liver disease, and metabolic liver injury.
- Primary biliary cholangitis
- Non-alcoholic steatohepatitis
- Liver cirrhosis
- Hepatic encephalopathy
- Cholestatic pruritus
He also participates in research relevant to pancreatic and gastrointestinal disorders, broadening the therapeutic scope across digestive medicine.
Oncology and Hematologic Malignancies
His trial involvement spans breast cancer, colorectal cancer, lung cancer, pancreatic cancer, and hepatocellular carcinoma, alongside hematologic malignancies such as multiple myeloma, acute lymphoblastic leukemia, and lymphoma. The portfolio also includes solid tumors with metastatic or unresectable disease.
- Breast cancer
- Colorectal cancer
- Pancreatic cancer
- Multiple myeloma
- Acute lymphoblastic leukemia
Research activity in this domain reflects a broad therapeutic interest in targeted oncology, immuno-oncology, and disease-specific treatment optimization.
Immune-Mediated, Dermatologic, and Rare Disorders
His clinical research also includes ulcerative colitis, Crohn’s disease, atopic dermatitis, psoriasis, hidradenitis suppurativa, and prurigo nodularis. Additional involvement extends to rare hematologic and systemic conditions such as hemophilia, sickle cell disease, and paroxysmal nocturnal hemoglobinuria.
- Ulcerative colitis
- Crohn’s disease
- Atopic dermatitis
- Hemophilia
- Paroxysmal nocturnal hemoglobinuria
He is also engaged in ophthalmic and inflammatory research, including age-related macular degeneration and glaucoma, supporting a wide therapeutic profile across immune and rare disease areas.
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